Housam Almadani, Mohammed Zein, Saleh Alzahrani, Mohammad Almelibari, Mohammed Elhefnawy, Soltan Hasan
{"title":"Case Report of High Dose Factor rVIIa in a Child","authors":"Housam Almadani, Mohammed Zein, Saleh Alzahrani, Mohammad Almelibari, Mohammed Elhefnawy, Soltan Hasan","doi":"10.61440/jcrcs.2023.v1.10","DOIUrl":null,"url":null,"abstract":"The maximum tolerated dose of recombinant factor VIIa without significant toxicity is not studied in a clinical trial. Separate case reports of accidental intake of high dose recombinant factor VIIa were reported. This case report describes an exposure of an infant with congenital factor VII deficiency to a high dose of recombinant factor VIIa (300 μg. /kg).","PeriodicalId":472378,"journal":{"name":"Journal of Clinical Research and Case Studies","volume":"27 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Clinical Research and Case Studies","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.61440/jcrcs.2023.v1.10","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
The maximum tolerated dose of recombinant factor VIIa without significant toxicity is not studied in a clinical trial. Separate case reports of accidental intake of high dose recombinant factor VIIa were reported. This case report describes an exposure of an infant with congenital factor VII deficiency to a high dose of recombinant factor VIIa (300 μg. /kg).
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