A Narrative Review on the Potential of Black Seeds (Nigella Sativa) in the Management of West Nile Virus Infection

IF 0.8 Q4 NUTRITION & DIETETICS

Current Nutrition & Food Science Pub Date : 2023-10-10 DOI:10.2174/0115734013251160230921114603

Naina Mohamed Pakkir Maideen, Rajkapoor Balasubramaniam, Arun Mulianur Shanmugam

{"title":"A Narrative Review on the Potential of Black Seeds (Nigella Sativa) in the Management of West Nile Virus Infection","authors":"Naina Mohamed Pakkir Maideen, Rajkapoor Balasubramaniam, Arun Mulianur Shanmugam","doi":"10.2174/0115734013251160230921114603","DOIUrl":null,"url":null,"abstract":"Abstract: West Nile virus (WNV) infection is a mosquito-borne illness that is endemic to Africa, Asia, the Middle East, Australia, and Europe. WNV-infected individuals can only be managed with symptomatic therapy and supportive care at this point of time. Thus, we have analyzed the possible beneficial effects of black seeds (N. sativa) in this literature review. To find relevant articles, various online databases, such as the Web of Science, Medline, PMC, PubMed, Embase, EBSCO, Google Scholar, Science Direct, and reference lists were searched. The antiviral, analgesic, anti-inflammatory, antioxidant, and immunomodulatory effects of black seeds (N. sativa) have been established by numerous clinical, animal, in vivo, in vitro, and in silico studies. It has been found that black seeds (N. sativa) have the potential to be included as adjuvant therapy in addition to symptomatic treatment and supportive care in the early stages of WNV infection once randomized controlled clinical trials (RCTs) affirm the safety and efficacy of black seeds (N. sativa) in WNV infection management as they have been considered the gold standard of treatment in clinical studies.","PeriodicalId":10944,"journal":{"name":"Current Nutrition & Food Science","volume":"30 1","pages":"0"},"PeriodicalIF":0.8000,"publicationDate":"2023-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Nutrition & Food Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/0115734013251160230921114603","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}

引用次数: 0

Abstract

Abstract: West Nile virus (WNV) infection is a mosquito-borne illness that is endemic to Africa, Asia, the Middle East, Australia, and Europe. WNV-infected individuals can only be managed with symptomatic therapy and supportive care at this point of time. Thus, we have analyzed the possible beneficial effects of black seeds (N. sativa) in this literature review. To find relevant articles, various online databases, such as the Web of Science, Medline, PMC, PubMed, Embase, EBSCO, Google Scholar, Science Direct, and reference lists were searched. The antiviral, analgesic, anti-inflammatory, antioxidant, and immunomodulatory effects of black seeds (N. sativa) have been established by numerous clinical, animal, in vivo, in vitro, and in silico studies. It has been found that black seeds (N. sativa) have the potential to be included as adjuvant therapy in addition to symptomatic treatment and supportive care in the early stages of WNV infection once randomized controlled clinical trials (RCTs) affirm the safety and efficacy of black seeds (N. sativa) in WNV infection management as they have been considered the gold standard of treatment in clinical studies.

查看原文本刊更多论文

黑籽(Nigella Sativa)在处理西尼罗病毒感染中的潜力述评

摘要:西尼罗病毒(WNV)感染是一种蚊媒疾病，流行于非洲、亚洲、中东、澳大利亚和欧洲。目前，西尼罗河病毒感染者只能通过对症治疗和支持性护理进行治疗。因此，我们对黑籽(N. sativa)可能的有益作用进行了文献综述。为了找到相关文章，我们搜索了各种在线数据库，如Web of Science、Medline、PMC、PubMed、Embase、EBSCO、Google Scholar、Science Direct和参考文献列表。黑籽(N. sativa)的抗病毒、镇痛、抗炎、抗氧化和免疫调节作用已被许多临床、动物、体内、体外和计算机研究证实。研究发现，一旦随机对照临床试验(RCTs)确认黑籽(N. sativa)在西尼罗河病毒感染管理中的安全性和有效性，黑籽(N. sativa)就有可能被纳入西尼罗河病毒感染早期阶段的辅助治疗，除了对症治疗和支持性护理之外，黑籽(N. sativa)被认为是临床研究中治疗的金标准。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Nutrition & Food Science NUTRITION & DIETETICS-

CiteScore

2.00

自引率

0.00%

发文量

144

期刊介绍： Current Nutrition & Food Science publishes frontier reviews on all the latest advances on basic and clinical nutrition and food sciences. The journal aims to publish the highest quality review articles dedicated to research in the field. The journal is essential reading for all nutrition and food scientists.