Effects of diets rich in monounsaturated fatty acids on the management and prevention of insulin resistance: A systematic review

IF 1 4区农林科学 Q4 CHEMISTRY, APPLIED

Grasas y Aceites Pub Date : 2023-10-10 DOI:10.3989/gya.1125212

E.L.L. Ramos, M.F.C. Lima, A.C.S.F. Azevedo, M.G.F. Lopes, A.P.B. Moreira, C.T. Souza

引用次数: 0

Abstract

Insulin resistance (IR), which is linked to obesity, is a mechanism associated with metabolic diseases, mainly type 2 diabetes mellitus. Studies have shown that monounsaturated fatty acids (MUFAs) have anti-inflammatory and anti-oxidative properties which positively affect IR. This systematic review examined the effects of MUFAs from different sources on IR in obese or overweight patients with or without metabolic syndrome. A search was carried out in the PubMed/Medline and Bireme/VHL databases, and data from 16 studies were analysed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The intervention time ranged from 1 day to 5.2 years. All participants were overweight or obese; some had central obesity, a moderate risk of cardiovascular disease, low high-density lipoprotein levels, altered fasting glucose levels, prediabetes or type 2 diabetes mellitus. This systematic review provides evidence that MUFA-rich diets can improve IR.

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富含单不饱和脂肪酸的饮食对胰岛素抵抗管理和预防的影响:一项系统综述

胰岛素抵抗(IR)与肥胖有关，是一种与代谢性疾病(主要是2型糖尿病)相关的机制。研究表明，单不饱和脂肪酸(MUFAs)具有抗炎和抗氧化特性，对IR有积极影响。本系统综述研究了不同来源的MUFAs对伴有或不伴有代谢综合征的肥胖或超重患者IR的影响。检索PubMed/Medline和Bireme/VHL数据库，并根据系统评价和荟萃分析指南的首选报告项目对16项研究的数据进行分析。干预时间为1天至5.2年。所有参与者都超重或肥胖;其中一些人患有中枢性肥胖，心血管疾病风险中等，高密度脂蛋白水平低，空腹血糖水平改变，患有前驱糖尿病或2型糖尿病。这一系统综述提供了富含mufa的饮食可以改善IR的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Grasas y Aceites 工程技术-食品科技

CiteScore

2.50

自引率

0.00%

发文量

审稿时长

3 months

期刊介绍： Grasas y Aceites is a peer-reviewed journal devoted to the publication of original articles concerning the broad field of lipids, especially edible fats and oils from different origins, including non acyl lipids from microbial origin relevant to the food industry. It publishes full research articles, research notes, reviews as well as information on references, patents, and books. Grasas y Aceites publishes original articles on basic or practical research, as well as review articles on lipid related topics in food science and technology, biology, (bio)chemistry, medical science, nutrition, (bio)technology, processing and engineering. Topics at the interface of basic research and applications are encouraged. Manuscripts related to by-products from the oil industry and the handling and treatment of the wastewaters are also welcomed. Topics of special interest to Grasas y Aceites are: -Lipid analysis, including sensory analysis -Oleochemistry, including lipase modified lipids -Biochemistry and molecular biology of lipids, including genetically modified oil crops and micro-organisms -Lipids in health and disease, including functional foods and clinical studies -Technical aspects of oil extraction and refining -Processing and storage of oleaginous fruit, especially olive pickling -Agricultural practices in oil crops, when affecting oil yield or quality