Effect of Omega3 for the Skin Diseases- A Review

Aoss Moez Abed –Alhussian Alyassery, Zainab Mahmood Al-Jammali, Anas Al-Yasiry
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 Objective: The review's objective is to provide a brief scientific overview of this condition, which has recently become widespread used in the treatment of skin diseases.
 Conclusion: The effects of \"3 PUFA\" in skin illnesses are only seldom studied in research and clinical trials, but prior studies analyzing immune cells predict that these fatty acids will have a wide range of positive benefits. Additionally, there are few findings on keratinocytes, which are thought to make up a significant portion of the epidermis' cells. Future studies should clarify the complete role keratinocytes play in the skin. since the prevalence of inflammatory skin conditions and cancers is rising at the moment, clinical trials in the future on \"3 PUFAs\" in dermatological sectors are likely to provide us with useful knowledge for the routine clinical management of skin problems.
 Keywords: Polyunsaturated fatty acids, \"PUFAs,\" omega-3, psoriasis, skin.","PeriodicalId":17505,"journal":{"name":"Journal of University of Babylon","volume":"40 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of University of Babylon","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.29196/jubpas.v31i3.4822","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract

Background: Omega3 is a group of fatty acids which is essential and of great importance to the human body, they cannot be produced on their own, so it must be obtained by following diets that include foods rich in them. Omega 3 is nowadays one of the most desirable components of oils because of its nutritional and functional properties. Through its various processes in cellular metabolism, its therapeutic actions in numerous chronic inflammatory and autoimmune disorders have been identified, gene expression, and signal transduction. Numerous studies have confirmed that acne, psoriasis, and inflammatory skin conditions including atopic dermatitis can all be managed with omega 3. Objective: The review's objective is to provide a brief scientific overview of this condition, which has recently become widespread used in the treatment of skin diseases. Conclusion: The effects of "3 PUFA" in skin illnesses are only seldom studied in research and clinical trials, but prior studies analyzing immune cells predict that these fatty acids will have a wide range of positive benefits. Additionally, there are few findings on keratinocytes, which are thought to make up a significant portion of the epidermis' cells. Future studies should clarify the complete role keratinocytes play in the skin. since the prevalence of inflammatory skin conditions and cancers is rising at the moment, clinical trials in the future on "3 PUFAs" in dermatological sectors are likely to provide us with useful knowledge for the routine clinical management of skin problems. Keywords: Polyunsaturated fatty acids, "PUFAs," omega-3, psoriasis, skin.
欧米茄3对皮肤病的作用综述
背景:欧米伽3是一组对人体至关重要的脂肪酸,它们不能自己产生,因此必须通过以下饮食获得,包括富含它们的食物。由于其营养和功能特性,欧米茄3是当今油脂中最理想的成分之一。通过其在细胞代谢中的各种过程,其在许多慢性炎症和自身免疫性疾病中的治疗作用已被确定,基因表达和信号转导。许多研究已经证实,痤疮、牛皮癣和包括特应性皮炎在内的炎症性皮肤状况都可以用omega - 3来治疗。目的:该综述的目的是提供一个简短的科学概述,这种情况最近已广泛用于治疗皮肤病。结论:“3 PUFA”对皮肤疾病的影响在研究和临床试验中很少被研究,但先前对免疫细胞的研究预测这些脂肪酸将具有广泛的积极益处。此外,很少有关于角化细胞的发现,角化细胞被认为是表皮细胞的重要组成部分。未来的研究应阐明角质形成细胞在皮肤中所起的完整作用。由于目前炎症性皮肤病和癌症的患病率正在上升,未来对皮肤病学领域“3种pufa”的临床试验可能会为我们提供皮肤问题的常规临床管理的有用知识。 关键词:多不饱和脂肪酸,PUFAs, omega-3,牛皮癣,皮肤
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