[Preparation and evaluation of an internal reference of oral polio vaccine].

Abstract

A trivalent working reference preparation for oral poliovaccine was prepared, and assayed over a period of three years; its stability at different temperatures was investigated. The results show that the batch of cryotubes is homogeneous and stable when stored frozen. The preparation, while containing no stabilizer is similar in composition with the vaccines to be tested and suitable to judge the acceptability of assays. The test system was shown to be accurate and reproducible.