[Recurrent hematuria in children: study of 250 cases].

H C Perrone, L de Moya, D Martini Filho, L A de Moura, V R de Mello, N Schor, J Toporovski
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Abstract

In order to analyse the etiology of recurrent hematuria in childhood, we studied 250 children, referred to our Service (age: 6 mo-17 ys; 102 female and 148 male). They were submitted to the following protocol: urine analyses, uroculture, serum total and fraction complement, electrophoresis of hemoglobin, serum creatinine, BUN, 24h urinary calcium, uric acid and protein, oral calcium load test in children with hypercalciuria (UCa greater than 4mg/kg/day). Radiological evaluation and renal percutaneous biopsy was performed when necessary. The following diagnostic distribution was obtained: Alport syndrome, 19; Berger disease, 15; other glomerulopathies, 45; hypercalciuria, 67; uric acid hyperexcretion, 10; nephrolithiasis, 27; urinary tract infection, 14; renal malformation, 8; no diagnosis, 43. Based in these results, we conclude that appropriate investigation on recurrent hematuria, leads to determination of etiology in over 80% of cases.

儿童复发性血尿250例分析
为了分析儿童复发性血尿的病因,我们研究了250名儿童,涉及我们的服务(年龄:6 mo-17 ys;102名女性和148名男性)。他们接受了以下方案:尿液分析、尿培养、血清总补体和部分补体、血红蛋白电泳、血清肌酐、尿素氮、24小时尿钙、尿酸和蛋白质、高钙尿症(UCa大于4mg/kg/天)儿童口服钙负荷试验。必要时行放射学评估及肾穿刺活检。诊断分布如下:Alport综合征19例;伯格氏病,15岁;其他肾小球疾病,45例;高钙尿,67;尿酸高排泄,10分;肾结石,27岁;尿路感染,14人;肾脏畸形,8分;没有诊断,43岁。基于这些结果,我们得出结论,对复发性血尿进行适当的调查,可以在80%以上的病例中确定病因。
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