A CASE REPORT ON MANAGEMENT OF FEMALE INFERTILITY DUE TO LOW ANTI MULLERIAN HORMONE WITH AYURVEDIC TREATMENT PROTOCOL

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Abstract

Complex series of events that are inevitable for a successful pregnancy include the formation of healthy sperm and ovum, their development and maturation, ovulation, fertilisation, transportation of fertilised ovum into the uterus, and implantation into a receptive uterine cavity. The recent trend of delaying conception may be associated with declining ovarian reserve, increasing the need for IVF with donor ovum. Anti mullerian Hormone *AMH+ is considered a surrogate marker for ovarian reserve and an indicator of healthy ovulation. So the reduced level of AMH is a great concern in the field of infertility management. Ayurveda emphasizes four main factors viz Rithu (ovulation), Kshetra (functional reproductive organs), Ambu (represents proper nutrition after fertilization, that can be correlated with corpus leuteal function upto the establishment of placenta and then onwards placental function), and Beeja (healthy sperm and ovum) which are essential for conception. Infertility due to Diminished ovarian reserve (DOR) can be considered under Dhatukshayajanya Vandhya explained in Harita Samhita. This case study focuses on a 27 year old female patient who approached came to OPD with complaints of inability to conceive even after 8 years of unprotected sexual life. A thorough history taking revealed that all infertility investigations were normal with the exception of the AMH count, which was found to be reduced. She was given medications for Agni deepana and Dhatuposhana as well as Panchakarma treatments, including Musthadi Rajayapana Vasti and Uttaravasti. With the abovementioned treatments for 3 courses, the patient approached our OPD, 2 months after discharge with the complaint of secondary amenorrhoea. The urine pregnancy test was found to be positive and the patient was advised for proper antenatal care and timely follow-up. She delivered a full-term healthy female baby on 14.9.23.
阿育吠陀治疗低抗苗勒管激素所致女性不育症一例报告
成功妊娠不可避免的一系列复杂事件包括健康精子和卵子的形成、发育和成熟、排卵、受精、受精卵进入子宫的运输以及植入接受子宫腔。最近推迟受孕的趋势可能与卵巢储备下降有关,增加了使用供体卵子进行体外受精的需求。抗苗勒管激素*AMH+被认为是卵巢储备的替代标志物和健康排卵的指标。因此,AMH水平的降低是不孕不育治疗领域关注的焦点。阿育韦达强调四个主要因素,即Rithu(排卵)、Kshetra(功能性生殖器官)、Ambu(代表受精后的适当营养,可与黄体功能相关,直至胎盘的形成,然后是胎盘功能)和Beeja(健康的精子和卵子),它们对受孕至关重要。根据Dhatukshayajanya Vandhya在Harita Samhita中解释的说法,由于卵巢储备减少(DOR)导致的不孕症可以考虑。本案例研究的重点是一位27岁的女性患者,她来到OPD,抱怨即使在8年无保护的性生活后仍无法怀孕。一个彻底的历史调查显示,所有不孕不育的调查是正常的,除了AMH计数,这是发现减少。她接受了Agni deepana和Dhatuposhana的药物治疗,以及Panchakarma治疗,包括Musthadi Rajayapana Vasti和Uttaravasti。患者经上述治疗3个疗程,出院2个月后以继发性闭经就诊。尿妊娠试验结果为阳性,建议患者进行适当的产前护理和及时随访。23年9月14日,她生下了一个足月健康的女婴。
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