A Rare but Sinister Case of Hodgkin Lymphoma Transforming into Large B-cell Lymphoma in HIV Infected Patient

Abstract

A dual diagnosis of cancer and HIV places a greater psychosocial burden on the patient. From a medical perspective, it complicates treatment for both diseases. Potential drug interactions, compounded side effects, and chemotherapy’s tendency to negatively impact CD4 count or HIV viral load, can all complicate treatment. It is imperative to advocate a keen and subtle vigilance while managing such patients to enhance the overall care for the patients. Here, we report such a case in a 36-year-old man who presented with HL as first manifestation of HIV infection that later transformed into DLBCL despite successful virologic suppression with ART