Evaluation of effectiveness of transcranial mesodiencephalic modulation within comprehensive treatment of pulmonary tuberculosis patients with various comorbidities

Abstract

The objective: to study the impact of transcranial mesodiencephalic modulation on eff ectiveness of comprehensive treatment of pulmonary tuberculosis patients with various comorbidities. Subjects and Methods. 48 patients who received standard regimens of anti-tuberculosis chemotherapy participated in the study; the patients were divided into two groups. In Group 1, patients additionally underwent sessions of mesodiencephalic modulation (MDM), while in Group 2, no MDM was administered. Results. Two months after the start of the study, in Group 1, positive radiological changes were recorded more often – in 91,7% (22/24), in Group 2, positive changes were observed in 62,5% (15/24) of patients ( p =0,047; χ2); the same pattern was observed with positive changes of laboratory rates – 91,7% (22/24) versus 66,7% (16/24), ( p =0,033; χ2), respectively. In patients of Group 1 compared to Group 2, symptoms of tuberculosis and comorbid conditions fully disappeared or became less intensive in 79,2% (19/24) versus 41,7% (10/24), ( p =0,009; χ2). In Group 1, adverse drug reactions were registered in 16,7% (4/24), in Group 2 – 43,5% (10/24), ( p =0,05; χ2).