Spectroscopic characterization, and anti-bacterial activity studies of the benzohydrazide derivatives complexes

Abstract

Five bivalent metal complexes of Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) with N-(4-(dimethylamino)benzylidene)benzohydrazide (HDmby) ligand with the general formula [M(Dmby) 2 (H 2 O) 2 ] {where M II = Co(1), Ni(2) and Cu(3)} and [M(Dmby) 2 ] {where MII= Zn(4), and Cd(5)} have been synthesized and characterized. The prepared complexes were characterized by 1 H NMR, IR spectrometry, UV–Vis spectra, Conductivity measurements, magnetic susceptibility. The Co(II), Ni(II) and Cu(II), complexes were found to have octahedral geometry, whereas the Zn(II) and Cd(II) complexes were of tetrahedral geometry. The anti-microbial activity of the synthesized complexes were investigated against three pathogenic bacteria using inhibition zone method and the order of activity of the complexes was determined to be [Zn(Dmby) 2 ] > [Cu(Dmby) 2 (H 2 O) 2 ] > [Ni(Dmby) 2 (H 2 O) 2 ] > [Co(Dmby) 2 (H 2 O) 2 ] > and [Cd(Dmby) 2 ].