Gout: A Possible Cause of Lumbal Canal Stenosis. Cases Report in Sub-Saharan Area and Literature Review

Alain Jibia, Bernard Azanmene, Arielle Lekane, Ernestine Bikono, Ignatius Esenee, Vincent-de-Paul Djientcheu
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Abstract

Introduction: Gout is defined as an arthritic condition resulting from the deposition of monosodium urate crystals in and/or around joints, following long-standing hyperuricemia. This may cause gouty arthritis in joints and tophi in soft tissues. Spinal gout is rare and never mentioned in our context. It can appear as acute back pain, radiculopathy, spinal cord compression, spondylodiscitis or neoplasic/infectious epiduritis. Our aim was to share our surgical experience and proceed of a Literature review. Cases Presentation: Between January and August 2022, two patients male were surgically cared, aged of 42 and 60 years old. The gout was unknown in the youngest and poorly followed in the eldest. There was no past medical history of tuberculosis or immunodeficiency in both. The early diagnosis retained was unspecific lumbar spondylodiscitis due to clinical features: Patients complained both of lower back pain with initial fever. It was of a progressive left L5S1 deficit with erectile defect and dysuria in the first case and a progressive paraplegia without sphincter disorders in the second case. We proceeded with a lumbar laminectomy with a biopsy on both patients. The spinal tophus was ligamentous in one case and arthro-ligamentous in the other. There was a progressive motor recovery from postoperative Day-2 till postoperative Month-1. A probabilistic antituberculosis treatment was promptly initiated postoperatively based on radioclinic features while waiting for histologic proof. The Polymerase Chain Reaction (PCR) of Mycobacterium tuberculosis was negative and the histology was of a chronic calcified osteitis with dense fibrosis in both. The anti-gout treatment was implemented after 15 days with blood test evidence. A rheumatologic follow-up was also initiated and adjuvant physio-therapy. The results were very satisfactory from 4 - 6 months with independent walking. Discussion Conclusion: Spinal Gout may be suggested in 40-male-old faced with any acute rachialgia with neuro deficit with dubious neuro-imaging.
痛风:腰椎管狭窄的可能原因。撒哈拉以南地区病例报告及文献综述
简介:痛风定义为长期高尿酸血症后,由尿酸钠晶体沉积在关节内和/或关节周围引起的关节炎。这可能会导致关节痛风性关节炎和软组织中的痛风石。脊柱痛风是罕见的,从未在我们的背景下提及。它可以表现为急性背痛,神经根病,脊髓压迫,脊柱炎或肿瘤/感染性硬膜外炎。我们的目的是分享我们的手术经验,并进行文献综述。病例介绍:2022年1月至8月,手术治疗男性2例,年龄42岁和60岁。最小的孩子不知道痛风的症状,而最大的孩子则很少受到关注。两组患者均无结核病或免疫缺陷病史。由于临床特征,保留的早期诊断为非特异性腰椎椎间盘炎:患者主诉腰痛伴首发发热。第一例为进行性左L5S1缺失伴勃起缺损和排尿困难,第二例为进行性截瘫,无括约肌功能障碍。我们对两名患者进行腰椎椎板切除术和活检。1例脊髓嵴为韧带性,另1例为关节韧带性。从术后第2天到术后第1个月,运动功能逐渐恢复。术后根据放射临床特征,在等待组织学证明的同时,立即开始了概率抗结核治疗。结核分枝杆菌聚合酶链反应(PCR)阴性,组织学表现为慢性钙化性骨炎伴致密纤维化。15天后进行抗痛风治疗,有血检证据。还开始了风湿病学随访和辅助物理治疗。术后4 ~ 6个月独立行走效果满意。结论:40岁男性,伴有神经影像学可疑的急性腰痛伴神经缺损者,可提示为脊髓性痛风。
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