CASE REPORT: “Boston type I keratoprosthesis with buccal mucosal overlay in severe chemical burn” ‘Barcelona CP’

Daniel Casado-López, Gloria Segura Duch, Víctor Lázaro-Rodríguez, Clara Álvarez de Toledo, Ainhoa Martínez-Grau, María Fideliz de la Paz
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Abstract

Objective To describe a case of severe chemical burn treated with a novel Boston type I keratoprosthesis (B1-KPro) technique. Methods We present the case of a 25-year-old woman with poor light perception in both eyes who had bilateral chemical burn with caustic soda 3 months earlier. She underwent several amniotic membrane implants and subconjunctival triamcinolone injections without significant improvement. We decided to perform a two-stage surgery on the right eye (RE). Reconstruction of the ocular surface was first performed using a buccal mucosa allograft. Nine months later the second surgical stage was performed, which consisted of partial lifting of the buccal mucosa, B1-KPro implantation covered with the buccal mucosa overlay and exposing the optics of the keratoprosthesis. Results Two days following surgery the uncorrected visual acuity (UCVA) was +0.2 logMAR. Best-corrected visual acuity (BCVA) at one month was 0,0 logMAR, remaining stable after one year and eleven months of follow-up. Conclusions Boston type 1 keratoprosthesis covered with buccal mucosa (B1-KPro with mucosa overlay technique) could be considered an alternative in severe ocular chemical burn with marked shortening of the fornix, as an alternative to osteo-odonto-keratoprosthesis (OOKP) or tibial bone keratoprosthesis or when the Boston type II keratoprosthesis is not available. It allows restoration of the anatomy and condition of the ocular surface using autologous tissue, with better aesthetics than OOKP and material easily available as it has the CE marking.
病例报告:“波士顿I型角膜假体伴颊粘膜覆盖治疗严重化学烧伤”巴塞罗那CP
目的介绍一种新型波士顿I型角膜假体(B1-KPro)技术治疗严重化学烧伤的病例。方法我们报告一位25岁的女性,双眼光感差,3个月前双侧烧碱化学烧伤。她接受了几次羊膜植入和结膜下曲安奈德注射,但没有明显改善。我们决定对右眼(RE)进行两阶段手术。眼表重建首先采用颊粘膜异体移植物。9个月后进行第二阶段手术,包括部分提升颊粘膜,B1-KPro植入覆盖颊粘膜,暴露角膜假体的光学。结果术后2 d未矫正视力(UCVA)为+0.2 logMAR。1个月最佳矫正视力(BCVA)为0 0 logMAR,随访1年11个月后保持稳定。结论口腔黏膜覆盖的Boston 1型角膜假体(B1-KPro与黏膜覆盖技术)可作为严重眼化学烧伤伴穹孔明显缩短的替代方案,作为骨-牙-角膜假体(OOKP)或胫骨角膜假体的替代方案,或当无法使用Boston II型角膜假体时。它允许使用自体组织修复眼表的解剖结构和状况,比OOKP具有更好的美观性,并且材料容易获得,因为它有CE标志。
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