A study of efficacy between interlaminar vs transforaminal approaches in symptomatic intervertebral disc herniations when treated with triamcinolone acetate

Q4 Biochemistry, Genetics and Molecular Biology
Dheeraj V. Kumar, Mithun Shetty, Bhaskar Bhandary, Manjunath S.
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Abstract

Introduction and Aim: With lumbar disc herniations occurring in the population at a rate of 2-3%, low back pain is one of the most common chronic pain syndromes. Since 1952, patients with failed medical and conservative therapy for lumbar radiculopathy in presence or absence of discogenic back pain have been treated using epidural corticosteroid injections. Triamcinolone acetate, a local steroid, limits the inflammatory response. Interlaminar, transforaminal and caudal routes are various approaches for steroid injections. This study compared the effectiveness of triamcinolone acetate injections administered via an interlaminar vs. transforaminal method. The aim was to contrast the transforaminal technique and interlaminar approach to triamcinolone acetate's effectiveness in relieving pain. Materials and Methods: In this study, 60 patients with low back pain are divided into two groups of 30 patients each and randomly allocated to receive care. Triamcinolone acetate solution, 40 mg, is used in each group. Interlaminar approach was chosen to inject the drug into the epidural space blindly, whereas through the transforaminal approach, the drug was delivered using dye with the help of fluoroscopic guidance. The outcome comprises evaluating pain reduction at the second and fourth weeks following the injection using a numerical scale and a verbal evaluation scale. Data was gathered after 15 minutes, at the 2nd and 4th week post injection. Results: Patients who received triamcinolone acetate via transforaminal route experienced greater pain reduction in terms of NRS and VAS at the second week. Conclusion: When comparing the NRS and VAS scores for pain alleviation, transforaminal is preferable to interlaminar because it delivers triamcinolone acetate to specific targets and is more successful than ILESI.
醋酸曲安奈德治疗症状性椎间盘突出症的椎间入路与经椎间孔入路的疗效研究
简介和目的:腰椎间盘突出症在人群中发生率为2-3%,腰痛是最常见的慢性疼痛综合征之一。自1952年以来,存在或不存在椎间盘源性背痛的腰椎神经根病的医学和保守治疗失败的患者一直使用硬膜外皮质类固醇注射治疗。醋酸曲安奈德,一种局部类固醇,限制炎症反应。椎间、椎间孔和尾侧途径是类固醇注射的不同途径。本研究比较了经椎间孔和经椎间孔注射醋酸曲安奈德的有效性。目的是比较经椎间孔技术和椎间入路对醋酸曲安奈德缓解疼痛的效果。材料与方法:本研究将60例腰痛患者随机分为两组,每组30例患者接受护理。每组使用醋酸曲安奈德溶液40 mg。选择椎间入路将药物盲目注入硬膜外腔,经椎间入路在透视引导下使用染料给药。结果包括在注射后第2周和第4周使用数字量表和口头评估量表评估疼痛减轻程度。注射后15分钟、第2周和第4周采集数据。结果:经椎间孔途径接受醋酸曲安奈德治疗的患者在第二周的NRS和VAS方面疼痛减轻更大。结论:在比较NRS和VAS评分时,经椎间孔比层间孔更能缓解疼痛,因为它能将醋酸曲安奈德传递到特定的靶点,比ILESI更成功。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biomedicine (India)
Biomedicine (India) Biochemistry, Genetics and Molecular Biology-Biochemistry, Genetics and Molecular Biology (all)
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153
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