Role of vaccination against COVID‑19

Abstract

Several vaccines from SARS-COV-2 are used in Russia, which have successfully passed all the stages of testing and showed their effectiveness. Purpose. The study was aimed to clarify the manifestations and course, severity of COVID-19 in SARS-CoV-2 vaccinated and unvaccinated patients. Materials and methods. 62 patients treated in an infectious hospital with a positive test for SARS-CoV-2 were examined. When selecting groups, the pseudorandomization method was used. Clinical symptoms of the disease, anamnesis data, results of pulse oximetry, computed tomography of the chest, clinical blood analysis, transaminase levels and hemostasis indicators were found out in all the examined patients. Results. The study showed that unvaccinated patients were hospitalized in a more serious condition, with significantly more pronounced volume of lung tissue damage and hypoxia. In the group of unvaccinated patients, there was a significantly higher incidence of liver damage and an increased risk of thrombosis. Unvaccinated patients had a significantly lower percentage of comorbid pathologies, and the vaccinated group was dominated by patients Conclusions. Vaccination from coronavirus infection does not exclude the development of the disease, but significantly reduces the frequency of its severe course.