INVESTIGATING THE VARIATIONS IN THE BRAIN ACTIVITY BETWEEN HEALTHY SUBJECTS AND MILD COGNITIVE IMPAIRMENT (MCI) PATIENTS

IF 3.3 3区数学 Q1 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS

Fractals-Complex Geometry Patterns and Scaling in Nature and Society Pub Date : 2023-10-11 DOI:10.1142/s0218348x23501244

NAJMEH PAKNIYAT, BALAMURALI RAMAKRISHNAN, V. PALLAVI, ONDREJ KREJCAR, ROBERT FRISCHER, HAMIDREZA NAMAZI

引用次数: 0

Abstract

Analysis of brain activity for patients with brain disorders is an important research area. Mild cognitive impairment (MCI) is a condition in which patients have more memory or thinking problems compared to healthy people of the same age. In this work, we studied the alterations in brain activity among control subjects and patients with MCI. Three complexity techniques, namely sample entropy, approximate entropy, and fractal dimension, were employed to study electroencephalogram (EEG) signals recorded from 102 control (healthy) subjects, and seven subjects with MCI in a comfortable position, on a bed, with their eyes closed. The results showed that the EEG signals of patients with MCI show greater complexity than the EEG signals of healthy subjects. This analysis method can be applied to compare brain activity among healthy subjects and patients with other brain diseases.

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研究健康受试者与轻度认知障碍(mci)患者脑活动的差异

脑功能障碍患者的脑活动分析是一个重要的研究领域。轻度认知障碍(MCI)是一种与同龄健康人群相比，患者有更多记忆或思维问题的疾病。在这项工作中，我们研究了对照组和轻度认知损伤患者的脑活动变化。采用样本熵、近似熵和分形维数三种复杂度技术对102名对照(健康)受试者和7名MCI患者在床上闭眼舒适体位时的脑电图(EEG)信号进行研究。结果表明，轻度认知损伤患者的脑电图信号比正常人的脑电图信号更复杂。这种分析方法可用于比较健康受试者和其他脑部疾病患者的大脑活动。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Fractals-Complex Geometry Patterns and Scaling in Nature and Society 数学-数学跨学科应用

CiteScore

7.40

自引率

23.40%

发文量

319

审稿时长

>12 weeks

期刊介绍： The investigation of phenomena involving complex geometry, patterns and scaling has gone through a spectacular development and applications in the past decades. For this relatively short time, geometrical and/or temporal scaling have been shown to represent the common aspects of many processes occurring in an unusually diverse range of fields including physics, mathematics, biology, chemistry, economics, engineering and technology, and human behavior. As a rule, the complex nature of a phenomenon is manifested in the underlying intricate geometry which in most of the cases can be described in terms of objects with non-integer (fractal) dimension. In other cases, the distribution of events in time or various other quantities show specific scaling behavior, thus providing a better understanding of the relevant factors determining the given processes. Using fractal geometry and scaling as a language in the related theoretical, numerical and experimental investigations, it has been possible to get a deeper insight into previously intractable problems. Among many others, a better understanding of growth phenomena, turbulence, iterative functions, colloidal aggregation, biological pattern formation, stock markets and inhomogeneous materials has emerged through the application of such concepts as scale invariance, self-affinity and multifractality. The main challenge of the journal devoted exclusively to the above kinds of phenomena lies in its interdisciplinary nature; it is our commitment to bring together the most recent developments in these fields so that a fruitful interaction of various approaches and scientific views on complex spatial and temporal behaviors in both nature and society could take place.