The Analysis of The Effectiveness of Pulmonary Tuberculosis and HIV-Co-TB Treatment Therapies at Sulianti Saroso Infectious Diseases Hospital

Nurita Andayani, Raise Maninda, Rosa Marlina, Qoina Noviantani, Khaled Qalalwa
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Abstract

Mycobacterium tuberculosis causes Tuberculosis (TB), an infectious disease. The study aims to evaluate DOTS therapy's impact on pulmonary TB and TB-HIV patients. This research used a descriptive qualitative study design with a retrospective descriptive research approach using secondary data for the period June 2017 to July 2020. The analysis uses the Miles and Huberman model. A study of 305 people found that 83% of pulmonary TB cases completed treatment within the initial phase, 64% completed the continuation phase. TB-HIV cases 93% completed treatment within the initial phase, 71% the continuation phase. The combination of OAT and ARV doses was successful in reducing initial smear conversion in pulmonary TB cases. The treatment was evaluated as cure in pulmonary TB cases, complete in pulmonary TB-HIV cases, and had no treatment failure status in both groups. Treatment success in pulmonary TB patients was not significantly related (p-value≥5%) with the type of OAT, type of PMO, gender, and age. Whereas in HIV co-infected pulmonary TB patients, treatment success was significantly related (p-value <5%) with the type of PMO, and not related (p-value≥5%) with the type of OAT, gender, and age.
苏连安蒂萨罗索传染病医院肺结核和艾滋病合并结核病治疗效果分析
结核分枝杆菌导致结核病(TB),一种传染病。该研究旨在评估DOTS治疗对肺结核和结核-艾滋病患者的影响。本研究采用描述性定性研究设计和回顾性描述性研究方法,使用2017年6月至2020年7月期间的二手数据。该分析使用了迈尔斯和休伯曼模型。一项对305人进行的研究发现,83%的肺结核病例在初始阶段完成了治疗,64%完成了继续治疗阶段。结核-艾滋病毒病例93%在初始阶段完成治疗,71%在继续阶段完成治疗。OAT和ARV联合剂量成功地减少了肺结核病例的初始涂片转化。治疗在肺结核病例中被评估为治愈,在肺结核- hiv病例中被评估为完全治疗,两组中没有治疗失败的情况。肺结核患者的治疗成功率与OAT类型、PMO类型、性别和年龄无显著相关(p值≥5%)。而在HIV合并感染肺结核患者中,治疗成功与PMO类型显著相关(p值<5%),与OAT类型、性别和年龄无关(p值≥5%)。
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26
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12 weeks
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