Active congenital toxoplasmosis, an underestimated threat: case report

Monica Holguin Barrera, Lorena García Agudelo, Sharon Briggitte Medina Barrera
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Abstract

Congenital toxoplasmosis (CT) is a consequence of vertical transmission of the toxoplasma gondii parasite during gestation. We present a case of premature CT, adolescent mother diagnosed in the second trimester of pregnancy with gestational toxoplasmosis, without treatment. After birth, the patient was admitted to the neonatal intermediate unit, with normal vital signs, on physical examination with mild signs of shortness of breath, splenomegaly approximately 7cm, hepatomegaly 3 cm, generalized micropapular lesions, chest X-ray without alteration and positive IgG and IgM serologies, confirming a severe CT diagnosis due to ocular, cerebral, hematologic and skin involvement; she received pyrimethamine, sulfadiazine, folinic acid and prednisolone. The appearance of these cases of severe component sets off alarms in prioritizing maternal and family education and also human talent at the time of approaching and monitoring the pregnant woman, contributing substantially to the decrease in vertical transmission, and in turn the long-term impact on the newborn and her family.
活动性先天性弓形虫病,一个被低估的威胁:病例报告
先天性弓形虫病(CT)是妊娠期间弓形虫寄生虫垂直传播的结果。我们提出了一个病例过早CT,青春期母亲诊断在妊娠中期妊娠弓形虫病,没有治疗。出生后,患者入住新生儿中级病房,生命体征正常,体格检查有轻度气短征象,脾肿大约7cm,肝肿大3cm,全身微丘疹病变,胸片无改变,IgG和IgM血清学阳性,确认因眼、脑、血液和皮肤受累的严重CT诊断;她接受乙胺嘧啶、磺胺嘧啶、亚叶酸和强的松龙治疗。这些严重病例的出现,在优先考虑孕产妇和家庭教育以及接近和监测孕妇时的人类才能方面敲响了警钟,大大有助于减少垂直传播,进而对新生儿及其家庭产生长期影响。
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