Investigating Verbal Repetition in Persian-speaking Patients with the Semantic Variant of Primary Progressive Aphasia Compared to Healthy Individuals

Abstract

Introduction: Language deficit is regarded as one of the most important hallmarks of primary progressive aphasia. This study aims to analyze the nature of verbal repetition ability in a group of patients suffering from the semantic variant of primary progressive aphasia and investigate their cognitive capability. Materials and Methods: In this cross-sectional study, 12 patients of the semantic variant of primary progressive aphasia and 12 healthy individuals accomplished a set of tasks, including naming, word comprehension, digit span, repetition of multisyllabic single words, monosyllabic word span under similar or dissimilar phonological conditions, and sentence repetition Results: The patients exhibited some degree of impairment with diverse patterns in each task, although the accomplishment of the sentence repetition task was the most challenging activity for the primary progressive aphasic patients of the semantic variant. However, the healthy individuals performed well in all tasks. Conclusion: The recognition of the quantity and quality of the cognitive deficit in the semantic variant of primary progressive aphasics can illuminate the nature of this disease and contribute to a better diagnosis of this disease. Furthermore, it can assist speech therapists and neuropsychologist to recruit appropriate therapies and employ better techniques for the diagnosis and cure of these patients.