Is post-ablation neo-squamous epithelium genomically predisposed to malignant progression?

Abstract

Radiofrequency ablation (RFA) is a frequently used treatment for dysplastic Barrett’s oesophagus or early oesophageal intramucosal carcinomas.[1 2][1] As a treatment, it is widely considered to be safe and effective at removing these aberrant lesions. The treated areas are re-populated with