Base-catalyzed Deprotection of Aldehyde: New Haloform Reaction

IF 2.2 4区 化学 Q2 CHEMISTRY, ORGANIC
Gulizhabaier Abulipizi, Kadierya Abuduwaili, Shiying Tian, Mailikezhati Maihemuti, Abudu Rexit Abulikemu
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引用次数: 0

Abstract

An efficient deprotection procedure for α,α,α-trihalogen (Cl, Br) methyl alcohols under mild reaction conditions to produce the high-performance liquid chromatography yield of series aldehydes and haloforms have been implemented. This can be applied to the de-protection of aromatic, aliphatic, and heterocyclic trihalomethyl alcohol compounds.

Abstract Image

碱催化醛脱保护:新卤仿反应
在温和反应条件下,对α,α,α-三卤(Cl, Br)甲醇进行了高效脱保护,得到了系列醛类和卤代化合物的高效液相色谱产率。这可以应用于芳族,脂肪族和杂环三卤甲醇化合物的去保护。
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来源期刊
Synthesis-Stuttgart
Synthesis-Stuttgart 化学-有机化学
CiteScore
4.50
自引率
7.70%
发文量
435
审稿时长
1 months
期刊介绍: SYNTHESIS is an international full-paper journal devoted to the advancement of the science of chemical synthesis. It covers all fields of organic chemistry involving synthesis, including catalysis, organometallic, medicinal, biological, and photochemistry, but also related disciplines. SYNTHESIS provides dependable research results with detailed and reliable experimental procedures and full characterization of all important new products as well as scientific primary data.
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