{"title":"Base-catalyzed Deprotection of Aldehyde: New Haloform Reaction","authors":"Gulizhabaier Abulipizi, Kadierya Abuduwaili, Shiying Tian, Mailikezhati Maihemuti, Abudu Rexit Abulikemu","doi":"10.1055/a-2201-3503","DOIUrl":null,"url":null,"abstract":"An efficient deprotection procedure for α,α,α-trihalogen (Cl, Br) methyl alcohols under mild reaction conditions to produce the high-performance liquid chromatography yield of series aldehydes and haloforms have been implemented. This can be applied to the de-protection of aromatic, aliphatic, and heterocyclic trihalomethyl alcohol compounds.","PeriodicalId":49451,"journal":{"name":"Synthesis-Stuttgart","volume":null,"pages":null},"PeriodicalIF":2.2000,"publicationDate":"2023-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Synthesis-Stuttgart","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1055/a-2201-3503","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
An efficient deprotection procedure for α,α,α-trihalogen (Cl, Br) methyl alcohols under mild reaction conditions to produce the high-performance liquid chromatography yield of series aldehydes and haloforms have been implemented. This can be applied to the de-protection of aromatic, aliphatic, and heterocyclic trihalomethyl alcohol compounds.
期刊介绍:
SYNTHESIS is an international full-paper journal devoted to the advancement of the science of chemical synthesis. It covers all fields of organic chemistry involving synthesis, including catalysis, organometallic, medicinal, biological, and photochemistry, but also related disciplines. SYNTHESIS provides dependable research results with detailed and reliable experimental procedures and full characterization of all important new products as well as scientific primary data.