Validation of the Paediatric Asthma Score (PAS) in Evaluation of Acute Exacerbation of Asthma in Children

Q4 Medicine
Joswin K Jose, Aparna Namboodiripad
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Abstract

Introduction: Assessing the severity of acute asthma objectively is important to guide treatment. Peak Expiratory Flow Rate (PEFR) is used for this. Paediatric Asthma Score (PAS) is a user-friendly asthma score in children. Our aim was to validate the efficacy of PAS in comparison with PEFR for assessing severity of acute asthma. Methods: The study included 32 children in the age group of five to 14 years, with mild to moderate asthma exacerbation. The PEFR and the PAS were measured before treatment, 15 min, 30 min, and one hour after treatment, and at discharge. Paired t-test was used to establish construct validity by comparing pre-and post-treatment PEFR and PAS. The criterion validity was calculated by correlating pre-and post-treatment PASs with PEFRs. Results: The mean predicted PEFR improved with treatment by 22.35% (p < 0.001) by one hour. Pre- and post-treatment PASs significantly correlated with PEFRs. The correlation of pre-treatment PEFR and PAS was r = -0.491 (p = 0.004), that for post-treatment at 1hour was r = -0.505 (p = 0.003). Conclusions: The study validities the PAS as a measure of severity of asthma. The PAS is thus a simple alternative to the PEFR to estimate airway obstruction in children within the age group to five to 14 years with acute asthma exacerbations.
儿科哮喘评分(PAS)在评估儿童哮喘急性加重中的有效性
简介:客观评估急性哮喘的严重程度对指导治疗具有重要意义。呼气流量峰值(PEFR)用于此。儿科哮喘评分(PAS)是一个用户友好的儿童哮喘评分。我们的目的是验证PAS与PEFR在评估急性哮喘严重程度方面的有效性。方法:本研究纳入32例5 ~ 14岁轻至中度哮喘加重的儿童。在治疗前、治疗后15分钟、30分钟、1小时和出院时测量PEFR和PAS。配对t检验通过比较治疗前后PEFR和PAS来确定结构效度。通过将治疗前和治疗后的PASs与pefr相关联来计算标准效度。 结果:经治疗后PEFR平均预测值提高22.35% (p <0.001)小时。治疗前后PASs与pefr显著相关。治疗前PEFR与PAS的相关性为r = -0.491 (p = 0.004),治疗后1h的相关性为r = -0.505 (p = 0.003)。 结论:该研究证实PAS可作为哮喘严重程度的衡量标准。因此,PAS是PEFR的一种简单替代方法,可用于估计5至14岁急性哮喘发作儿童的气道阻塞。
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来源期刊
Journal of Nepal Paediatric Society
Journal of Nepal Paediatric Society Medicine-Pediatrics, Perinatology and Child Health
CiteScore
0.20
自引率
0.00%
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0
审稿时长
12 weeks
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