Investigating how Interleukin 6 Serum Level, Blood Group Type, and Underlying Diseases are Associated in Patients Admitted to the COVID-19 Intensive Care Unit: A Retrospective Study

Q3 Nursing

Open Public Health Journal Pub Date : 2023-10-12 DOI:10.2174/0118749445258188230922115257

Zahra Abbasi, Ali Moghadaci, Leila Mohammadnahal, Faezeh Hoseini Sangrizeh, Mohammad Hossein Gholami, Reza Baeelashaki, Kiavash Hushmandi, Rasoul Raesi, Asma Khalilipour, Shahriar Dashti

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引用次数: 0

Abstract

Aims: This study intended to examine correlations between interleukin 6 serum levels, blood group, and underlying disease in patients admitted to the COVID-19 intensive care unit. Background: Understanding the relationship between a patient's blood group, underlying disease(s), and the body's cytokine reactions is essential for care provision to COVID-19 patients. Materials and Methods: The clinical records of 31 patients admitted to an intensive care unit were analyzed using a census method. Data were collected using a researcher-developed checklist and analyzed with SPSS-22 statistical software using one-way analysis of variance and Tukey-Kramer post hoc, independent t, and multiple regression. The level of significance was set to p <0.05. Results: The mean serum level of interleukin 6 was significantly higher in patients with blood type B and those with two or more underlying diseases (p <0.05). The mean serum interleukin 6 levels in patients differed significantly based on the history of COVID-19 vaccine injection and the length of hospitalization (p <0.05). The mean serum interleukin 6 levels were associated with the length of COVID-19 intensive care unit stay and survival (p <0.05). Conclusion: Effective and timely care provision for COVID-19 patients is a top priority, which can be achieved by understanding the correlation between the body's cytokine reactions in the fight against COVID-19, blood type, and underlying diseases.

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调查COVID-19重症监护病房入院患者血清白细胞介素6水平、血型和基础疾病的相关性:一项回顾性研究

目的:本研究旨在探讨COVID-19重症监护病房住院患者血清白细胞介素6水平、血型和基础疾病之间的相关性。背景:了解患者血型、基础疾病和身体细胞因子反应之间的关系对于为COVID-19患者提供护理至关重要。材料与方法:对我院重症监护病房收治的31例患者的临床资料进行统计分析。使用研究者自行开发的检查表收集数据，并使用SPSS-22统计软件进行单因素方差分析和Tukey-Kramer事后、独立t和多元回归分析。显著性水平设为p <0.05。结果:B型血及伴有两种及两种以上基础疾病的患者血清白细胞介素6 (interleukin 6)的平均水平明显高于B型血(p <0.05)。不同疫苗注射史和住院时间的患者血清平均白细胞介素6水平差异有统计学意义(p <0.05)。平均血清白细胞介素6水平与COVID-19重症监护病房住院时间和生存率相关(p <0.05)。结论:及时有效地为COVID-19患者提供护理是当务之急，这可以通过了解人体细胞因子反应与血型和基础疾病之间的关系来实现。

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来源期刊

Open Public Health Journal Social Sciences-Health (social science)

CiteScore

1.00

自引率

0.00%

发文量

期刊介绍： The Open Public Health Journal is an Open Access online journal which publishes original research articles, reviews/mini-reviews, short articles and guest edited single topic issues in the field of public health. Topics covered in this interdisciplinary journal include: public health policy and practice; theory and methods; occupational health and education; epidemiology; social medicine; health services research; ethics; environmental health; adolescent health; AIDS care; mental health care. The Open Public Health Journal, a peer reviewed journal, is an important and reliable source of current information on developments in the field. The emphasis will be on publishing quality articles rapidly and freely available worldwide.