PHARMACOGNOSTICAL AND PHYTOCHEMICAL EVALUATION OF A POLYHERBAL ANTIHYPERTENSIVE AYURVEDIC FORMULATION [NIA/DG/2015/01]

Abstract

Introduction: Hypertension is a complex clinical illness with a frequency of 40.8 percent in the urban Indian population and 17.9 percent in the rural population. Multiple antihypertensives are used to treat hypertension. However, many have adverse effects and are hazardous. NIA/DG/2015/01 is a polyherbal antihypertensive ayurvedic ghan formulation, containing Arjuna (Terminalia arjuna Roxb.), Ashwagandha (Withania somnifera Linn.), Jatamansi (Nardostachys jatamansi DC.), Shankhpushpi (Convolvulus pluricaulis Choisy.), Punarnava (Boerhavia diffusa Linn.). Aim and objective: To evaluate a polyherbal antihypertensive Ayurvedic formulation [NIA/DG/2015/01] in terms of pharmacognosy, physiochemistry, phytochemistry and chromatography. Materials and methods: A polyherbal antihypertensive ayurvedic formulation [NIA/DG/2015/01] was evaluated for purity, safety, and quality using pharmaco-gnostical, physiochemical, phytochemical, and chromatographic methods. Observations and Results: The pharmaco-gnostical, physiochemical, phytochemical, and chromatographic results were within normal limits per API. Conclusion: The present sample of a polyherbal antihypertensive ayurvedic formulation [NIA/DG/2015/01] met quality standards for purity, safety and authenticity.