Cerebellopontine angle tumours: clinico-radiological features and surgical outcome

Vivek Kumar Kankane, Ketan Gujral, Avinash Sharma, Aditya Shrivastava
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 Materials and method. This is a prospective study of 40 patients at the Department of Neurosurgery, Jayarogya Group of Hospitals, GRMC Gwalior, M.P. India. All of the patients were pre-operatively evaluated with either non-enhanced and enhanced computerized tomography (CT) or Magnetic-resonance (MR) imaging or both.CPA tumours (predominantly acoustic neuroma) that underwent surgical removal using a suboccipital retro sigmoid approach over a 2-year period (June 2019 to May 2021).
 Results. There was a female preponderance. The most common presentation was Sensorineural hearing loss (90%) followed by Headache (67.5%). The majority of cases of Vestibular Schwannoma have heterogenous enhancement with cystic component.65% of patients have large (26-40mm) size tumours and facial nerve preservation is 86.4% in medium size tumours (10-25 mm).and Incidence of post-postoperative of facial nerve palsy is more in Giant size tumour (> 40mm) so Positive association between size of lesion and Incidence of Post-operative facial nerve palsy. CSF leak occurs in 6 patients and postoperative Hydrocephalus occur in 2 patients and Mortality occurs in 3 patients.
 Conclusion. CP angle Tumor was common in middle age group, with the incidence in females slightly more than in males. The majority of lesions were of large size (26-40mm). Most of the patients on admission had a non-serviceable hearing. Heterogeneous enhancement with cystic components was found in most of the lesions. Gross-total excision was one in the majority of cases and vestibular schwannoma was the most common histopathological lesion obtained. Facial nerve palsy was the most complication and as the size of the lesion increased, the possibility of facial nerve palsy also increased post-operatively. Overall mortality is 7.5%.","PeriodicalId":30188,"journal":{"name":"Romanian Neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Romanian Neurosurgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33962/roneuro-2023-042","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract

Object. Our aim is to demonstrate the various aspects of clinical-Radiological presentation and surgical Outcome with association to the tumour size concerning cerebellopontine angle (CPA) tumours. Materials and method. This is a prospective study of 40 patients at the Department of Neurosurgery, Jayarogya Group of Hospitals, GRMC Gwalior, M.P. India. All of the patients were pre-operatively evaluated with either non-enhanced and enhanced computerized tomography (CT) or Magnetic-resonance (MR) imaging or both.CPA tumours (predominantly acoustic neuroma) that underwent surgical removal using a suboccipital retro sigmoid approach over a 2-year period (June 2019 to May 2021). Results. There was a female preponderance. The most common presentation was Sensorineural hearing loss (90%) followed by Headache (67.5%). The majority of cases of Vestibular Schwannoma have heterogenous enhancement with cystic component.65% of patients have large (26-40mm) size tumours and facial nerve preservation is 86.4% in medium size tumours (10-25 mm).and Incidence of post-postoperative of facial nerve palsy is more in Giant size tumour (> 40mm) so Positive association between size of lesion and Incidence of Post-operative facial nerve palsy. CSF leak occurs in 6 patients and postoperative Hydrocephalus occur in 2 patients and Mortality occurs in 3 patients. Conclusion. CP angle Tumor was common in middle age group, with the incidence in females slightly more than in males. The majority of lesions were of large size (26-40mm). Most of the patients on admission had a non-serviceable hearing. Heterogeneous enhancement with cystic components was found in most of the lesions. Gross-total excision was one in the majority of cases and vestibular schwannoma was the most common histopathological lesion obtained. Facial nerve palsy was the most complication and as the size of the lesion increased, the possibility of facial nerve palsy also increased post-operatively. Overall mortality is 7.5%.
桥小脑角肿瘤:临床放射学特征和手术结果
对象。我们的目的是展示与桥小脑角(CPA)肿瘤大小相关的临床影像学表现和手术结果的各个方面。 材料和方法。这是一项前瞻性研究,40名患者在神经外科,Jayarogya集团医院,GRMC Gwalior, mp印度。所有患者术前均通过非增强和增强计算机断层扫描(CT)或磁共振成像(MR)或两者进行评估。CPA肿瘤(主要是听神经瘤)在2年期间(2019年6月至2021年5月)采用枕下乙状窦逆行入路手术切除。 结果。女性占多数。最常见的表现是感音神经性听力损失(90%),其次是头痛(67.5%)。大多数前庭神经鞘瘤具有囊性成分的异质强化。65%的患者为大肿瘤(26-40mm),中等肿瘤(10- 25mm)的面神经保存率为86.4%。巨大肿瘤术后面神经麻痹发生率较高(>病变大小与术后面神经麻痹发生率呈正相关。脑脊液漏6例,术后脑积水2例,死亡3例。 结论。CP角肿瘤多见于中年人,女性发病率略高于男性。多数病变尺寸较大(26 ~ 40mm)。大多数入院患者的听力都不正常。大多数病变均呈囊性增强。绝大多数病例均行大体全切除,而前庭神经鞘瘤是最常见的组织病理病变。面神经麻痹是最常见的并发症,随着病变面积的增加,术后面神经麻痹的可能性也增加。总死亡率为7.5%。
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