Micro gas chromatography column coated with ionic liquid/metal-organic framework composites as the stationary phase

IF 2.4 4区工程技术 Q2 ENGINEERING, ELECTRICAL & ELECTRONIC

Journal of Micromechanics and Microengineering Pub Date : 2023-09-22 DOI:10.1088/1361-6439/acf93e

Kangning Zhang, Xinyu Wu, Dazuo Wang, Xinyuan Hua, Ze Zhang, Peng Li, Bing Tian, Hairong Wang, Jianhai Sun

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引用次数: 0

Abstract

Abstract In this paper, the μ GC-IL/MOF and the μ GC-IL were prepared using [P66614][NTf 2 ]/ZIF-8 and [P66614][NTf 2 ] as the stationary phase, respectively. [P66614][NTf 2 ]/ZIF-8 composite stationary phase material has high specific surface area and porous structure, which increases the diffusion of gas molecules in the column. Compared to μ GC-IL, μ GC-IL/MOF can separate n-alkanes mixture (C5–C12) and lung cancer biomarkers (pentane, isoprene, acetone, benzene, 2-pentanone) with higher resolution, and the resolution ( R ) of pentane and isoprene was increased by 257.00% in particular. The μ GC-IL/MOF can separate lung cancer biomarkers in about 5 min with optimal carrier gas velocity and column temperature. The retention times of pentane, isoprene, acetone, benzene, and 2-pentanone were 0.884 min, 1.246 min, 1.634 min, 2.204 min, and 3.049 min, respectively. The resolutions of adjacent peaks were 1.785, 1.525, 2.521, and 3.514, respectively. Which meets the requirements of quantitative analysis ( R > 1.5). Therefore, the μ GC-IL/MOF is expected to be integrated into portable devices for environmental monitoring and medical diagnosis in the future.

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微气相色谱柱包被离子液体/金属-有机骨架复合材料作为固定相

摘要以[P66614][NTf 2]/ZIF-8和[P66614][NTf 2]为固定相，制备了μ GC-IL/MOF和μ GC-IL。[P66614][NTf 2]/ZIF-8复合固定相材料具有高比表面积和多孔结构，增加了柱内气体分子的扩散。与μ GC-IL相比，μ GC-IL/MOF能以更高的分辨率分离正构烷烃混合物(C5-C12)和肺癌标志物(戊烷、异戊二烯、丙酮、苯、2-戊酮)，其中戊烷和异戊二烯的分辨率(R)提高了257.00%。在最佳载气速度和柱温条件下，μ GC-IL/MOF可在约5 min内分离出肺癌标志物。戊烷、异戊二烯、丙酮、苯和2-戊酮的保留时间分别为0.884 min、1.246 min、1.634 min、2.204 min和3.049 min。邻峰分辨率分别为1.785、1.525、2.521、3.514。满足定量分析的要求(R >1.5)。因此，μ GC-IL/MOF有望在未来集成到便携式环境监测和医疗诊断设备中。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Micromechanics and Microengineering 工程技术-材料科学：综合

CiteScore

4.50

自引率

4.30%

发文量

136

审稿时长

2.8 months

期刊介绍： Journal of Micromechanics and Microengineering (JMM) primarily covers experimental work, however relevant modelling papers are considered where supported by experimental data. The journal is focussed on all aspects of: -nano- and micro- mechanical systems -nano- and micro- electomechanical systems -nano- and micro- electrical and mechatronic systems -nano- and micro- engineering -nano- and micro- scale science Please note that we do not publish materials papers with no obvious application or link to nano- or micro-engineering. Below are some examples of the topics that are included within the scope of the journal: -MEMS and NEMS: Including sensors, optical MEMS/NEMS, RF MEMS/NEMS, etc. -Fabrication techniques and manufacturing: Including micromachining, etching, lithography, deposition, patterning, self-assembly, 3d printing, inkjet printing. -Packaging and Integration technologies. -Materials, testing, and reliability. -Micro- and nano-fluidics: Including optofluidics, acoustofluidics, droplets, microreactors, organ-on-a-chip. -Lab-on-a-chip and micro- and nano-total analysis systems. -Biomedical systems and devices: Including bio MEMS, biosensors, assays, organ-on-a-chip, drug delivery, cells, biointerfaces. -Energy and power: Including power MEMS/NEMS, energy harvesters, actuators, microbatteries. -Electronics: Including flexible electronics, wearable electronics, interface electronics. -Optical systems. -Robotics.