A study on quality of life and contrast sensitivity pre and post laser assisted in situ keratomileusis (LASIK) between subjects with low, moderate and high myopia: A prospective, NEI-RQL 42 questionnaire based study

Venugopal Anitha, Aditee Madkaikar, Meenakshi Ravindran, Sandeep Bachu, MohammedSithiq Uduman
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Abstract

Purpose: To assess the quality of life and contrast sensitivity (CS) pre- and post-laser assisted in situ keratomileusis (LASIK) among subjects with low, moderate and high myopia. Materials: A total of 95 ubjects undergoing myopic LASIK during the study period from 2018 to 2019 among different grades of myopia were included. It was a prospective, non-randomised study. Quality of life was measured by NEI-RQL 42 (national eye institute refractive error quality of life) questionnaire. The Pelli-Robson chart measured contrast sensitivity and the visual outcomes before LASIK and at one week, one month and six months after LASIK. Results: One hundred and ninety eyes of 95 subjects were included in the study. Out of these, 93.5% of low myopia (n = 29/31), 85.7% of moderate myopia (n = 36/42) and 72.7% of high myopia (n = 16/22) improved to 6/6 at six month follow up. All 13 subscales of the NEI-RQL 42 questionnaire observed an increasing trend except glare (GL) which showed a decreasing trend over time, and the results were statistically significant at a 5% level. Concerning contrast sensitivity, low myopias had a better postoperative CS when compared to high myopia, and this finding was statistically significant (P = 0.012). Conclusion: Despite being a safe and effective procedure of refractive correction, LASIK has its setbacks, especially when compared with the quality of vision, and this can be minimized by careful preoperative assessment and in-depth patient counseling by the treating physicians.
低、中、高度近视患者LASIK手术前后的生活质量和对比敏感度研究:一项基于NEI-RQL 42问卷的前瞻性研究
目的:评价低、中、高度近视患者LASIK手术前后的生活质量和对比敏感度(CS)。资料:纳入2018 - 2019年研究期间不同度数的近视LASIK患者95例。这是一项前瞻性、非随机研究。生活质量采用NEI-RQL 42 (national eye institute屈光不正生活质量)问卷进行测量。Pelli-Robson图表测量了LASIK手术前、术后一周、一个月和六个月的对比敏感度和视力结果。结果:95名受试者共190只眼纳入研究。其中93.5%的低近视(n = 29/31)、85.7%的中度近视(n = 36/42)和72.7%的高度近视(n = 16/22)在随访6个月时改善至6/6。NEI-RQL 42问卷的13个分量表除眩光(GL)随时间呈下降趋势外,其余均呈上升趋势,且在5%的水平上具有统计学显著性。对比敏感度方面,低近视眼术后CS优于高度近视眼,差异有统计学意义(P = 0.012)。结论:尽管LASIK是一种安全有效的屈光矫正手术,但它也有缺点,特别是与视力质量相比,这可以通过仔细的术前评估和治疗医生对患者的深入咨询来最大限度地减少。
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18 weeks
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