Synthesis of biopolymer-polypeptide conjugates and their potential therapeutic interests

Abstract

Abstract Biopolymer-based conjugates are widely used for numbers of biomedical applications. Materials scientists have become progressively interested in compounding biological-relevant entities with biopolymers into polymeric biohybrid framework. Biopolymer are conjugated with various fragments such as enzymes, proteins, nucleic acids as well as their analogues, peptidomimetics, peptides, fluorescent composites, avidin or streptavidin, biotin, polyethylene glycol, and various other bioactive compounds in order to serve a particular functionality in biomedical applications. In current chapter, a summary of various methods to synthesize biopolymer-peptide biohybrid conjugates and their prospective applications in biomedical field is presented.