[Immunochemical study of modified forms of L-asparaginase].

M F Iulaev, D M Ivnitskiĭ, A P Kashkin, T Ia Bogdanova, A S Korsakova
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Abstract

Certain catalytic and immunological properties of L-asparaginase modified by polyglucin were studied. It was shown that the modified forms of L-asparaginase maintained high catalytic activity (Km 0.80.10(-5)-1.89.10(-5) M) and at the same time appeared to be more resistant to inactivation under the effect of antibodies.

l -天冬酰胺酶修饰形式的免疫化学研究。
研究了聚葡聚糖修饰l -天冬酰胺酶的催化和免疫特性。结果表明,改性后的l -天冬酰胺酶保持了较高的催化活性(Km 0.0.810 (-5)-1.89.10(-5) M),同时在抗体作用下表现出更强的抗失活能力。
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