Study of antimicrobial property of knitted spacer fabric treated with 1-Tetradecanaminium, N,N-dimethyl-N-[3-(trimethoxysilyl)propyl], chloride

Abstract

The current study helps to understand the efficacy of antimicrobial treatment done on a weft-knitted spacer fabric. The antimicrobial agent used in the study is from the class of quaternary ammonium salts. The fabric is evaluated for antimicrobial efficacy. It is also cross-compared with the drug and some advanced wound dressings available in the market for its antimicrobial and anti-biofilm activity. Knitted spacer fabric treated with 1-Tetradecanaminium, N,N-dimethyl-N-[3-(trimethoxysilyl)propyl], chloride (QAS) shows good antimicrobial properties and is shown to exhibit a broad range of antimicrobial effects against gram-positive bacteria, gram-negative bacteria and also fungus and yeast. The rapidity of killing and durability of microbial activity make it a very suitable material for infection control in applications like wound care materials. The spacer fabric can behave as foam in the management of exudates in wounds. The efficacy of this material compared with other dressing materials yields substantial evidence of its activity as a wound dressing material when it comes to management of microbial contaminations including biofilm prevention and disruption. Such material can find use in the management of chronic wounds and is a subject matter of further studies with clinical evidence.