Nilesh Kodali, Isabella Blanchard, Keshav D. Kumar, Mallory Zaino, Steven R. Feldman
{"title":"The Influence of Psoriasis on Type 2 Diabetes Mellitus Patient Profiles: A National Inpatient Sample Study","authors":"Nilesh Kodali, Isabella Blanchard, Keshav D. Kumar, Mallory Zaino, Steven R. Feldman","doi":"10.1177/24755303231212153","DOIUrl":null,"url":null,"abstract":"Background Psoriasis is believed to be a common comorbidity of type 2 diabetes mellitus (T2DM). Little is known on the impact psoriasis has on T2DM patients’ disease profiles. Objective To assess the impact psoriasis has on T2DM patients’ demographics, comorbidities, and health care outcomes. Methods We retrospectively analyzed the 2017 U.S. National Inpatient Sample (NIS) database. We utilized ICD-10 codes to determine T2DM and psoriasis patients along with associated comorbidities. Continuous variables were compared by independent-sample t-tests and categorical variables were compared via Pearson chi-square. All analysis were conducted in IBM SPSS 25. Results Among 7,705,988 T2DM admissions, 0.67% of them had comorbid psoriasis. T2DM psoriasis patients (64.38; SD: 12.403) were, on average, younger (64.38 vs 66.73; P < .001) and white (78.7% vs 63.1%; P < .001) and had increased foot ulcers (4.2% vs 3.8%; P < .001), hyperglycemia (22.4% vs 21.0%; P < .001), retinopathy (22.4% vs 21.0%; P < .001), hypercoagulopathy (8.5% vs 6.9%; P < .001), and hypertension (72.5% vs 70.4%; P < .001) than T2DM patients without psoriasis. T2DM psoriasis patients spent more days in the hospital (5.49 vs 5.37; P < .001), had more concurrent diagnoses (19.05 vs 16.5; P < .001), less total charges ($60,596.71 vs $61,534.66; P = 0.010) and had less in-hospital deaths (2.0% vs 2.7%; P < .001) than T2DM patients without psoriasis. Conclusions The presence of comorbid psoriasis significantly impacts T2DM patients’ demographics, comorbidities, and health care outcomes. These findings underscore the importance of early disease monitoring, cross-specialty collaboration, and medication monitoring in order to guide individualized management strategies and optimize patient care.","PeriodicalId":36656,"journal":{"name":"Journal of Psoriasis and Psoriatic Arthritis","volume":"12 5","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2023-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Psoriasis and Psoriatic Arthritis","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/24755303231212153","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Background Psoriasis is believed to be a common comorbidity of type 2 diabetes mellitus (T2DM). Little is known on the impact psoriasis has on T2DM patients’ disease profiles. Objective To assess the impact psoriasis has on T2DM patients’ demographics, comorbidities, and health care outcomes. Methods We retrospectively analyzed the 2017 U.S. National Inpatient Sample (NIS) database. We utilized ICD-10 codes to determine T2DM and psoriasis patients along with associated comorbidities. Continuous variables were compared by independent-sample t-tests and categorical variables were compared via Pearson chi-square. All analysis were conducted in IBM SPSS 25. Results Among 7,705,988 T2DM admissions, 0.67% of them had comorbid psoriasis. T2DM psoriasis patients (64.38; SD: 12.403) were, on average, younger (64.38 vs 66.73; P < .001) and white (78.7% vs 63.1%; P < .001) and had increased foot ulcers (4.2% vs 3.8%; P < .001), hyperglycemia (22.4% vs 21.0%; P < .001), retinopathy (22.4% vs 21.0%; P < .001), hypercoagulopathy (8.5% vs 6.9%; P < .001), and hypertension (72.5% vs 70.4%; P < .001) than T2DM patients without psoriasis. T2DM psoriasis patients spent more days in the hospital (5.49 vs 5.37; P < .001), had more concurrent diagnoses (19.05 vs 16.5; P < .001), less total charges ($60,596.71 vs $61,534.66; P = 0.010) and had less in-hospital deaths (2.0% vs 2.7%; P < .001) than T2DM patients without psoriasis. Conclusions The presence of comorbid psoriasis significantly impacts T2DM patients’ demographics, comorbidities, and health care outcomes. These findings underscore the importance of early disease monitoring, cross-specialty collaboration, and medication monitoring in order to guide individualized management strategies and optimize patient care.
背景银屑病被认为是2型糖尿病(T2DM)的常见合并症。银屑病对2型糖尿病患者疾病概况的影响知之甚少。目的评估银屑病对2型糖尿病患者的人口统计学、合并症和卫生保健结果的影响。方法回顾性分析2017年美国国家住院患者样本(NIS)数据库。我们使用ICD-10代码来确定T2DM和牛皮癣患者及其相关合并症。连续变量的比较采用独立样本t检验,分类变量的比较采用Pearson卡方检验。所有分析均在IBM SPSS 25中进行。结果在入院的7705988例T2DM患者中,合并牛皮癣的占0.67%。2型糖尿病银屑病患者(64.38;SD: 12.403)平均年轻(64.38 vs 66.73;P & lt;.001)和白色(78.7% vs 63.1%;P & lt;.001),足部溃疡增加(4.2% vs 3.8%;P & lt;.001),高血糖(22.4% vs 21.0%;P & lt;.001),视网膜病变(22.4% vs 21.0%;P & lt;.001),高凝血功能障碍(8.5% vs 6.9%;P & lt;.001),高血压(72.5% vs 70.4%;P & lt;.001)高于无牛皮癣的T2DM患者。2型糖尿病银屑病患者住院天数较多(5.49 vs 5.37;P & lt;.001),并发诊断较多(19.05 vs 16.5;P & lt;.001),总收费较低(60,596.71美元对61,534.66美元;P = 0.010),住院死亡率更低(2.0% vs 2.7%;P & lt;.001)高于无牛皮癣的T2DM患者。结论合并症银屑病的存在显著影响T2DM患者的人口统计学、合并症和卫生保健结果。这些发现强调了早期疾病监测、跨专业合作和药物监测的重要性,以指导个性化管理策略和优化患者护理。