Helicobacter pylori relationship in cases of coexistence of gastritis and gallbladder disease

Acıbadem üniversitesi sağlık bilimleri dergisi Pub Date : 2023-09-23 DOI:10.31067/acusaglik.1325344

Ramazan UÇAK, Ozlem TON ERYİLMAZ, Ömer Faruk DİLBAZ, Cemal KAYA, Banu YILMAZ ÖZGÜVEN, Emir ÇAPKINOĞLU, Fevziye KABUKCUOĞLU

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Abstract

Purpose: We aimed to investigate the effect of Helicobacter Pylorii (HP) on the development of gallbladder diseases and cholelithiasis and its relationship with gastritis. Methods: 282 gastritis cases with follow-up and operated gallbladder material were included in the study. All histomorphological findings, presence of HP and other variables were compared. Active inflammation and presence of HP were examined in the gastritis group. The gallbladder (GB) disease group was evaluated in terms of cholelithiasis, inflammation, cholesterolosis, intestinal and pyloric metaplasia, and the presence of HP. Results: Gallbladder HP (+) was higher in female patients than in male patients. The presence of HP in the GB was significantly higher in patients with cholelithiasis than patients without cholelithiasis. The incidence of HP in the GB was higher in patients with active gastritis than in patients with inactive gastritis. The presence of HP in the GB was found to be higher in patients with HP on gastric biopsy. HP was found to be less in cases without cholesterolosis in the GB (p

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幽门螺杆菌在胃炎和胆囊疾病共存病例中的关系

目的:探讨幽门螺杆菌(Helicobacter pylori, HP)在胆囊疾病和胆石症发生中的作用及其与胃炎的关系。方法:对282例胃炎患者进行随访和胆囊切除术。比较所有组织形态学结果、HP的存在和其他变量。胃炎组检查活动性炎症和HP的存在。胆囊(GB)疾病组以胆石症、炎症、胆固醇沉着、肠道和幽门化生、HP的存在进行评估。结果:女性患者胆囊HP(+)高于男性患者。胆石症患者的GB中HP的存在明显高于非胆石症患者。活动性胃炎患者胃壁HP的发生率高于非活动性胃炎患者。胃活检发现HP患者的GB中HP的存在更高。在没有胆固醇的情况下，HP在GB中被发现较少(p

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