Confronting Leptospirosis: A Tropical Illness Presenting with Thrombotic Microangiopathy and Multiorgan Dysfunction

Arnab Choudhury, Ajinkya Rahatgaonkar
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Abstract

This case report outlines the presentation and clinical course of a 28-year-old lady with previously unremarkable health, who developed symptoms including fever, headache, gastrointestinal distress, and jaundice. Her condition rapidly deteriorated, culminating to multisystem involvement in the form of severe anaemia, acute kidney injury, thrombocytopenia, and acute respiratory distress syndrome (ARDS). The aetiology was confirmed as leptospirosis. Despite optimum therapeutic measures, including mechanical ventilation and plasmapheresis in view of suspected thrombotic microangiopathy, the patient succumbed to the complications of severe ARDS. This case underscores the imperative of early identification and tailored management strategies for intricate multi-system involvement in conditions like leptospirosis.
面对钩端螺旋体病:一种表现为血栓性微血管病变和多器官功能障碍的热带疾病
本病例报告概述了一名28岁女性的表现和临床过程,她以前的健康状况并不明显,她出现的症状包括发烧、头痛、胃肠不适和黄疸。她的病情迅速恶化,最终以严重贫血、急性肾损伤、血小板减少症和急性呼吸窘迫综合征(ARDS)的形式累及多系统。病因确诊为钩端螺旋体病。尽管采取了最佳的治疗措施,包括机械通气和血浆置换,考虑到可疑的血栓性微血管病,患者还是死于严重的ARDS并发症。该病例强调了在钩端螺旋体病等复杂的多系统参与情况下,早期识别和量身定制管理策略的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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