Analgesia in childbirth - comparison and analysis of the classical technique of epidural analgesia and modified with puncture of the dura mater

Ye.M. Sulimenko
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Abstract

Epidural analgesia (EA), most commonly used for labor analgesia, is an effective and relatively safe technique, but may be associated with slow onset, inadequate block. The use of Dural puncture epidural (DPE) is designed to find a balance between improving the quality of analgesia and reducing the frequency of side effects. Purpose - to compare two methods of labor analgesia. Materials and methods. All women (n=80) were divided into two groups: the Group I (n=40) used DPE, the Group II (n=40) used EA. In both groups, the same technique of epidural puncture and catheterization was used, in the Group I additionally puncture of the dura mater. Analgesia was evaluated using the visual analog pain rating scale (VAS). The quality and effectiveness of analgesia, the hemodynamics of the woman were evaluated. Complications and unwanted effects were recorded. Fetal condition: cardiotocography (CTG), umbilical cord blood lactate, pH. A statistical analysis of the obtained data was carried out. Results. The first contraction (VAS1) in the Group I were fixed on 11.43.3 min, and in the Group II on 21.57.2 min (p0.05). Monolateral block in the Group I - 4 (10%) versus 10 (25%) (p0.05). Contractions (VAS 1) after 30 min in the Group II - 7 (17.5%) versus the absence of such in the Group I. Stroke volume in the Group I decreased by 2.1% versus 1.5% in the Group II. The data for hypotension and occurrence of complications, CTG, cord blood lactate, and pH were not different by group. Conclusions. The use of the DPE technique against EA gives better results in terms of the quality and effectiveness of analgesia. The mother’s hemodynamics remained stable when using DPE. The DPE technique does not increase the frequency of complications compared to EA. There was no difference between the groups when assessing the state of the fetus according to CTG data, pH indicators and umbilical cord blood lactate. The research was carried out in accordance with the principles of the Helsinki Declaration. The study protocol was approved by the Local Ethics Committee of participating institution. The informed consent of the patient was obtained for conducting the studies. No conflict of interest was declared by the author.
分娩镇痛:经典硬膜外镇痛与改良硬脑膜穿刺镇痛的比较分析
硬膜外镇痛(EA)最常用于分娩镇痛,是一种有效且相对安全的技术,但可能与缓慢起效,阻滞不充分有关。硬膜外穿刺(DPE)的使用是为了在提高镇痛质量和减少副作用发生率之间找到平衡。目的:比较两种分娩镇痛方法。材料和方法。所有女性(n=80)分为两组:I组(n=40)采用DPE, II组(n=40)采用EA。两组均采用相同的硬膜外穿刺和置管技术,I组在硬脑膜外加穿刺。采用视觉模拟疼痛评定量表(VAS)评价镇痛效果。对镇痛的质量、效果、血流动力学进行评价。记录并发症及不良反应。胎儿状况:心动图(CTG)、脐带血乳酸、ph值。对所得数据进行统计分析。结果。第一组第一次收缩(VAS - )固定在11.43.3 min,第二组固定在21.57.2 min (p < 0.05)。1 - 4组单侧阻滞(10%)vs 10组(25%)(p 0.05)。II - 7组30分钟后的收缩(VAS - )(17.5%)与I组无收缩相比,I组的脑卒中容量减少2.1%,而II组减少1.5%。各组低血压及并发症发生率、CTG、脐带血乳酸、pH值无显著差异。结论。使用DPE技术对抗EA在镇痛质量和有效性方面取得了更好的结果。使用DPE时,母亲的血流动力学保持稳定。与EA相比,DPE技术没有增加并发症的发生频率。在根据CTG数据、pH指标和脐带血乳酸水平评估胎儿状态时,两组之间没有差异。这项研究是按照《赫尔辛基宣言》的原则进行的。本研究方案经参与单位当地伦理委员会批准。获得患者的知情同意进行研究。作者未声明存在利益冲突。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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