Role of speech–Language pathologist in rehabilitation in an individual with dysarthria in medically diagnosed case of Alexander disease – A single case report

Abstract

Alexander disease is a rare nervous system disorder resulting from GFAP gene mutation, cause dysarthria in children to adults. A comprehensive language and speech including voice, articulation, and speech intelligibility assessment were carried out before providing speech therapy. The result indicated a poor maintenance of voice and articulation with hypernasality, making the speech more unintelligible. However, after sessions of speech therapy, improvement was observed with reduced hypernasality, improved articulation, and overall speech intelligibility.