Influence of Selephlan on the morphohistological structure of the liver of the Arbor Acres cross poultry

M. P. Semenenko, A. A. Abramov, E. P. Dolgov, K. A. Semenenko, E. V. Kuzminova
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Abstract

The intensification of growing processes, concentrated feeding and other improvements in technological processes in poultry farms have led to the development of new metabolic pathologies for the industry, previously not widely recorded. The development of these diseases is directly related to excessive stress on the poultry body during intensive rearing. The central organ most susceptible to this type of stress is the liver. Currently, clear signs of hepatopathy are recorded even in poultry farming. As a result, an important offal – the liver – is discarded, the poultry lags behind in growth and development, and the quality of the meat decreases. Therefore, the development of hepatoprotective veterinary drugs for poultry farming is an urgent task. To determine the effectiveness of the new hepatoprotective drug Selephlan in the vivarium conditions of the Federal State Budgetary Scientific Institution “Krasnodar Research Centre for Animal Husbandry and Veterinary Medicine”, an experiment was conducted on two groups of broiler chickens (experimental and control) of the Arbor Acres cross (n=100). The studied drug was given to the experimental group during the growth and finishing periods of rearing (15–40 days) at a dose of 1.0% per unit of feed. The poultry of the control group received complete feed (CF) without additives. In order to determine the state of the hepatobiliary system of poultyr in the end of the experimental period, intravital screening monitoring of the liver condition using ultrasound diagnostics was carried out in the experimental and control groups, followed by slaughter to clarify the identified changes in the liver parenchyma tissue. Based on ultrasound diagnostics and histological studies, it was determined that the drug Selephlan under conditions of intensive fattening allows maintaining the healthy structure and functional activity of the liver of broiler chickens at a physiologically normal level throughout the entire productive period of rearing, which has a beneficial effect on the growth characteristics of meat poultry and the quality of the resulting livestock products.
Selephlan对爱拔益加杂交家禽肝脏形态组织结构的影响
家禽养殖场中生长过程的集约化、集中饲养和其他技术过程的改进导致了该行业新的代谢病理的发展,这在以前没有广泛记录。这些疾病的发生与集约化饲养过程中对家禽机体的过度应激有直接关系。最易受这种压力影响的中枢器官是肝脏。目前,甚至在家禽养殖中也记录到明显的肝病迹象。结果,一种重要的内脏——肝脏——被丢弃,家禽的生长发育滞后,肉的质量下降。因此,研制保肝兽药是一项紧迫的任务。为了确定新型护肝药物Selephlan在联邦国家预算科学机构“克拉斯诺达尔畜牧和兽医研究中心”的动物条件下的有效性,对两组爱拔益加杂交肉鸡(n=100)进行了试验(实验和对照)。试验组在饲养的生长期和育肥期(15 ~ 40 d)按每单位饲料1.0%的剂量给药。对照组饲喂不含添加剂的全饲饲料(CF)。为了确定试验结束时家禽肝胆系统的状态,我们对试验组和对照组进行了超声诊断对肝脏状况的活体筛查监测,然后屠宰以澄清所识别的肝脏实质组织的变化。基于超声诊断和组织学研究,我们确定在强化育肥条件下,Selephlan药物可以使肉鸡肝脏的健康结构和功能活性在整个育肥生产期间保持在生理正常水平,这对肉禽的生长特性和畜产品的质量有有益的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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