Effects of a full-body electrostimulation garment application in a cohort of subjects with cerebral palsy, multiple sclerosis, and stroke on upper motor neuron syndrome symptoms

IF 1.3 4区医学 Q4 ENGINEERING, BIOMEDICAL

Biomedical Engineering / Biomedizinische Technik Pub Date : 2023-09-12 DOI:10.1515/bmt-2023-0271

Andreas Hahn, Susan Moeller, Arne Schlausch, Matilda Ekmann, Gautier de Chelle, Marie Westerlund, Frank Braatz, Winfried Mayr

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引用次数: 0

Abstract

Abstract Objectives Dysfunction of the central nervous system may inflict spastic movement disorder (SMD). Electrical stimuli were identified as promising therapeutic option. Electrical stimulation provided by a 58-electrode full body garment was investigated based on data from regular trial fittings. Methods Data from 72 testees were investigated. Age averages 36.6 (19.8) ys with 44 females. The cohort spans infantile cerebral paresis (CP) (n=29), multiple sclerosis (MS) (n=23) and stroke (n=20). Data were stratified by etiology and an entry BBS Score<45. Results Effect sizes (Cohen`s d) related BBS, TUG, FGA, 10mWT, WMFT, EQ5D5L and Pain. Significance levels are indicated by *: p<0.05, **: p<0.01, ***: p<0.001, (t): p<0.1: CP: 1.64***, 0.29*, 1.59***, 0.76(t), 1.00***, 0.5*, 1.28***; MS: 1.83***, 0.83***, 1.28**, 1.07***, 0.93*, 1,11**, 0.78*; Stroke: 1.28**, 0.78**, 0.89, 0.92**, 0.71, 1.26*, 0.78*. Conclusions Multi-site transcutaneous electrical stimulation may increase ambulation related skills in subjects with SMD stemming from CP, MS and stroke. The results indicate effects on static and dynamic balance, fall risk, mobility, upper extremity improvement and an overall increase in health utility and a reduction in spasticity related pain. Effects are immediate as well as sustained. These results may inspire individual trial fittings and inform further controlled trials.

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在脑瘫、多发性硬化症和中风患者队列中应用全身电刺激衣对上运动神经元综合征症状的影响

目的中枢神经系统功能障碍可引起痉挛性运动障碍(SMD)。电刺激被认为是有希望的治疗选择。基于常规试装的数据，研究了58个电极的全身服装所提供的电刺激。方法对72名被试进行资料调查。平均年龄36.6岁(19.8岁)，女性44名。该队列包括婴儿脑性轻瘫(CP) (n=29)、多发性硬化症(MS) (n=23)和中风(n=20)。数据按病因和BBS评分进行分层。结果效应量(Cohen’s d)与BBS、TUG、FGA、10mWT、WMFT、EQ5D5L和Pain相关。重要性水平是由*表示:术;0.05 * *:术;0.01 * * *:术中,0.001,(t):术;0.1:CP: 1.64 * * * 0.29 * 1.59 * * *, 0.76 (t), 1.00 * * * 0.5 * 1.28 * * *;女士:1.83 * * *,* * * 0.83,1.28 * * 1.07 * * * 0.93 * 1,11 * * 0.78 *;中风:1.28 * *,* * 0.78,0.89,0.92 * *,0.71,1.26 * 0.78 *。结论多部位经皮电刺激可提高脑瘫、多发性硬化症和脑卒中所致SMD患者的行走相关技能。结果表明，在静态和动态平衡、跌倒风险、活动能力、上肢改善、健康效用的总体增加和痉挛相关疼痛的减少方面都有影响。影响是即时的，也是持续的。这些结果可能会启发个体试验，并为进一步的对照试验提供信息。

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来源期刊

Biomedical Engineering / Biomedizinische Technik 医学-工程：生物医学

CiteScore

3.50

自引率

5.90%

发文量

审稿时长

2-3 weeks

期刊介绍： Biomedical Engineering / Biomedizinische Technik (BMT) is a high-quality forum for the exchange of knowledge in the fields of biomedical engineering, medical information technology and biotechnology/bioengineering. As an established journal with a tradition of more than 60 years, BMT addresses engineers, natural scientists, and clinicians working in research, industry, or clinical practice.