Lipid profile of postmenopausal women

Q4 Medicine
Dunja Šojat, Romana Marušić, Klara Ormanac, Saška Marczi, Tatjana Bačun
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Abstract

Objectives: The main objectives of the research are to examine the incidence of hyperlipoproteinemia in postmenopausal women and to determine the differences in lipid profile considering age, duration of menopause and body mass index in postmenopausal women. Respondents and methods: The research is structured as cross-sectional with historical data. The research used data collected during regular check-ups in primary health care clinics in Osijek Health Center from November 2021 to March 2022. Collected data: demographic data, information on the duration of menopause, body mass, body height, body mass index, values of total, LDL, HDL cholesterol and triglycerides, and data on associated diseases. Results: 98 postmenopausal women were included in the research, of which over 50% had elevated total and LDL cholesterol values, and 39.8% had elevated triglyceride values. Subjects aged 45 to 65 years and subjects with a duration of menopause of 10 or more years had significantly higher values of total and LDL cholesterol while no difference was observed in the lipid profile with regard to the body mass index. Using the SCORE2 table, it was estimated that 65% of the subjects had a very high cardiovascular risk, and only 6% of the subjects achieved the target values of LDL cholesterol in accordance with the cardiovascular risk. Conclusion: There is a very high incidence of hyperlipoproteinemia in postmenopausal women, and the age and duration of menopause have an impact on the poorer achievement of the target values of the lipid profile, while the body mass index showed no impact. Given the high prevalence of subjects with a very high cardiovascular risk (SCORE 2 tables), intensive interventions are needed at all levels of health care, especially at the primary level of health care, which include non-pharmacological and pharmacological methods of treating hyperlipoproteinemia.
绝经后妇女的脂质谱
目的:本研究的主要目的是检查绝经后妇女高脂蛋白血症的发生率,并确定绝经后妇女在考虑年龄、更年期持续时间和体重指数的情况下血脂谱的差异。调查对象和方法:本研究采用历史数据横截面结构。该研究使用了2021年11月至2022年3月期间在奥西耶克卫生中心初级卫生保健诊所定期检查期间收集的数据。收集的数据:人口统计数据、更年期持续时间、体重、身高、体重指数、总胆固醇、低密度脂蛋白、高密度脂蛋白胆固醇和甘油三酯的值以及相关疾病的数据。结果:98名绝经后妇女纳入研究,其中总胆固醇和低密度脂蛋白胆固醇升高超过50%,甘油三酯升高39.8%。年龄在45岁到65岁之间的受试者和绝经10年或更长时间的受试者的总胆固醇和低密度脂蛋白胆固醇值明显较高,而与体重指数相关的脂质谱没有观察到差异。根据SCORE2表,估计65%的受试者有非常高的心血管风险,只有6%的受试者达到了与心血管风险相符的LDL胆固醇目标值。结论:绝经后妇女高脂血症发生率非常高,绝经年龄和绝经时间对血脂指标较差达标有影响,而体重指数无影响。鉴于高心血管风险受试者的高患病率(SCORE 2表),各级卫生保健,特别是初级卫生保健,需要强化干预措施,包括治疗高脂蛋白血症的非药物和药物方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medica Jadertina
Medica Jadertina Medicine-Medicine (all)
CiteScore
0.10
自引率
0.00%
发文量
38
期刊介绍: Medica Jadertina magazine contains scientific and professional papers covering a wide range of themes in the fields of biomedicine and health, psychology, pharmaceutics, public health and health insurance. Scientific areas: Biomedicine and health; Public health and health care; Pharmaceutics; Psychology.
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