Sulfamic Acid Supported Zr-MOF: An Effective Catalyst for One-Step Synthesis of Novel 6-Amino-5-(4-Amino-2-Oxo-2H-Chromen) Analogs

Abstract

Sulfamic acid-functionalized Zr-MOF-NH₂ was used as an active acidic metal-organic framework catalyst for the synthesis of new 6-amino-5-(4-amino-2-oxo-2H-chromen) (AAOC) analogs via a one-step reaction between 2-hydroxy-5-(aryldiazenyl)benzaldehyde, 4-aminocumarin, and 6-amino-1,3-dimethyluracil or 6-amino-uracil in EtOH under reflux conditions. The resulting UiO-66-NHSO₃H was characterized by employing different types of spectroscopic techniques such as XRD, BET, FESEM, EDS, FT-IR, and TGA. In addition, ease of procedure, short reaction time, and recycling of the catalyst without much change in the catalytic activity are the advantages of this method.