Pedunculated left endoventricular thrombosis complicated by cerebral stroke in patient with suspected peripartum cardiomyopathy: A case report

Kristian Galanti, Roberta Magnano, Laura Pezzi, Mario Di Marino, Alberto D’ Alleva, Daniele Forlani, Piergiusto Vitulli, Vincenzo Di Egidio, Gabriele Di Giammarco, Leonardo Paloscia, Sabina Gallina, Massimo Di Marco
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Abstract

Peripartum cardiomyopathy (PPMC) is an infrequent form of cardiomyopathy, whose main presentation is characterized by systolic dysfunction that commonly emerges in the early postpartum period. Acute heart failure symptoms such as congestion and dyspnea are common manifestations of PPMC. Here, we present a case of a 32-year-old female who, after hospitalization, manifested dyspnea and thoracic pain linked to the findings a left endoventricular thrombus. After the admission to the intensive cardiovascular care unit, heart failure and anticoagulant therapies as well as non-steroidal anti-inflammatory drugs were administered, leading to initial improvement of the left ventricular global function. Five days after the treatment, the patient experienced aphasia and right hemiplegia. The cerebral angiography documented an M1 segment occlusion. After treating the occlusion with stent retriever thrombectomy, the symptoms regressed and she attained full recovery. Therefore, surgical thrombectomy should be prioritized as the treatment approach to removing the pedunculated left ventricular thrombus, considering the apical morphology of the pedunculated left ventricular thrombus and if the anticoagulant therapy gives rise to side effects.
疑似围产期心肌病患者伴有带蒂左室内血栓形成并发脑卒中1例
围产期心肌病(PPMC)是一种少见的心肌病,其主要表现为收缩功能障碍,通常出现在产后早期。急性心力衰竭症状如充血和呼吸困难是PPMC的常见表现。在这里,我们提出一个32岁的女性病例,住院后,表现为呼吸困难和胸痛,与左室内血栓的发现有关。入住心血管重症监护室后,给予心力衰竭、抗凝治疗及非甾体类抗炎药治疗,左心室整体功能初步改善。治疗5天后,患者出现失语和右偏瘫。脑血管造影显示M1段闭塞。经支架取栓治疗闭塞后,症状消退,患者完全康复。因此,考虑到带蒂左心室血栓的根尖形态以及抗凝治疗是否会产生副作用,应优先考虑手术取栓作为去除带蒂左心室血栓的治疗方法。
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来源期刊
自引率
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期刊介绍: Chinese Journal of Geriatric Heart Brain and Vessel Diseases (monthly) was founded in 1999. It is a medical professional academic journal published domestically and internationally and is supervised by China Rongtong Medical Health Group Co., Ltd. and sponsored by Rongtong Medical Health Journal Publishing (Beijing) Co., Ltd. It mainly reports on the latest research results and research progress of professional academic hotspots such as clinical diagnosis and treatment of elderly cardiovascular and cerebrovascular diseases. The main columns include expert reviews, guidelines and consensus, guidelines and suggestions, expert forums, meeting minutes, clinical research, basic research, short reports, experience exchange, academic trends, case reports, reviews, and continuing education. Over the years, it has always adhered to the purpose of serving the development of geriatric medicine, so that the journal has been continuously improved and improved in terms of journal quality and academic level, and gradually gained recognition and praise from medical experts. Chinese Journal of Geriatric Heart Brain and Vessel Diseases is a high-quality Chinese scientific journal, a core journal in the clinical medicine/special medicine category of the 2023 edition of the "Overview of Chinese Core Journals", and a statistical source journal for Chinese scientific papers (Chinese core scientific journals). It is included in the "Compendium of High-Quality Scientific and Technological Journal Classification Catalog" released by the China Association for Science and Technology in 2023, and is included in the World Journal Impact Index (WJCI) report (2023 Science and Technology Edition). It is also included in more than 10 domestic and foreign databases such as the World Health Organization (WHO) and the American Chemical Abstracts.
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