Impact of Type 2 Diabetes Mellitus on Pulmonary Function Tests

Q3 Pharmacology, Toxicology and Pharmaceutics
Ruaa Abdulsaid, Azza Sajid, Talib Kadhim Akar
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引用次数: 0

Abstract

Background: Diabetes mellitus is a chronic metabolic disorder that may affect different organs including the lungs. Different studies have been published on the effects of diabetes mellitus on pulmonary function. A restrictive pattern of lung disorder was reported in some studies, whereas an obstructive pattern was suggested in others. The study aims to determine the impact of type 2 diabetes on pulmonary function tests (PFTs) and the type of respiratory disorder. Material and Methods: This observational study was conducted in Basrah City, Iraq. One hundred and eighty-two participants were enrolled and divided into 2 groups: 100 healthy (group1) and 82 patients with type2 diabetes mellitus (group 2).PFTs were estimated by a medical spirometer and measurements of several hematological tests were done for each individual. Results: We found a significant decline (p >0.05) in each of FEV1, FVC, PEF, and MVV and a significant increase in ELA in group 2. The restrictive pulmonary disorder was a higher percentage (24.39%) than obstruction (10.9%) and combined (2.43%). Conclusion: Pulmonary function tests were significantly affected by type2 DM and the percentages of different respiratory disorders were higher among group 2 than in group 1, with an increase in restrictive pattern.
2型糖尿病对肺功能试验的影响
背景:糖尿病是一种慢性代谢性疾病,可累及包括肺在内的不同器官。关于糖尿病对肺功能的影响已有不同的研究发表。在一些研究中报告了限制性肺疾病,而在其他研究中则提出了阻塞性肺疾病。该研究旨在确定2型糖尿病对肺功能测试(PFTs)和呼吸系统疾病类型的影响。材料和方法:本观察性研究在伊拉克巴士拉市进行。182名参与者被分为两组:100名健康患者(第一组)和82名2型糖尿病患者(第二组)。pft由医用肺活量计估算,并对每个人进行多项血液学检查。结果:2组FEV1、FVC、PEF、MVV均显著下降(p >0.05), ELA显著升高(p >0.05)。限制性肺疾病的比例(24.39%)高于梗阻(10.9%)和合并(2.43%)。结论:2型糖尿病对肺功能有明显影响,2型糖尿病组患者出现各种呼吸系统疾病的比例均高于1型糖尿病组,且限制模式增加。
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来源期刊
Iraqi Journal of Pharmaceutical Sciences
Iraqi Journal of Pharmaceutical Sciences Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)
CiteScore
1.40
自引率
0.00%
发文量
37
审稿时长
24 weeks
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