Androgenetic alopecia updates: Pathophysiology, diagnosis and treatment

Asmaa Tarek Farouk, Lamia Hamouda Elgarhy, Shady Fikry Abdelsalam, Dareen Abd Elaziz Mohamed, Fatma Abd El Ghafar Abd Rabo
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Abstract

Androgenetic alopecia (AGA) is a hereditary disorder characterized by the presence of hair follicles that exhibit sensitivity to androgens. The manifestations and progression of androgenetic alopecia are contingent upon the relationship between endocrine variables and genetic predisposition. Androgenetic alopecia is distinguished by the gradual reduction in size of hair follicles, resulting from the influence of androgens on the epithelial cells of hair follicles that are genetically predisposed and located in androgen-sensitive regions. There are varieties of medical, surgical and light‐based treatment options available to slow or reverse the progression of AGA, some of these treatments are relatively new and still to be explored.
雄激素性脱发最新进展:病理生理学、诊断和治疗
雄激素性脱发(AGA)是一种以毛囊对雄激素敏感为特征的遗传性疾病。雄激素源性脱发的表现和进展取决于内分泌变量和遗传易感性之间的关系。雄激素性脱发的特点是毛囊大小逐渐缩小,这是由于雄激素对毛囊上皮细胞的影响,这些细胞是遗传易感性的,位于雄激素敏感区域。有各种各样的药物、手术和基于光的治疗方案可用于减缓或逆转AGA的进展,其中一些治疗方法相对较新,仍有待探索。
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