COVID-19 and Diabetes: Acknowledging the Bidirectional Link

Bangabandhu Sheikh Mujib Medical University Journal Pub Date : 2023-10-13 DOI:10.3329/bsmmcj.v1i2.69349

Mohammad Rezaul Quader, Mohammad Jahidur Rahman Khan, Arifa Akram, Md Shahidul Islam, Nusrat Mannan, Md Sabir Hossain, Nurul Karim, Farha Matin Juliana, Amirul Huda Bhuiyan, Paroma Deb, Farhana Khatoon, Farzana Mim, Md Selim Reza

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Abstract

COVID-19 and diabetes mellitus have a dynamic and bidirectional relationship. Diabetes is a risk factor for COVID19. Diabetes mellitus is linked to hypercoagulability, inflammation, hyperglycemia, and other conditions (obesity, hypertension, cardiovascular disease, chronic kidney disease). Hyperglycemia may worsen SARS-CoV-2 infection. As a result of direct pancreatic damage caused by COVID-19, the stress response is triggered response to infection (including cytokine storm), including the use of hyperglycemic prescription medications such as corticosteroids for severe COVID-19, new-onset hyperglycemia and diabetes have been linked to the virus, as well as rapidly deteriorating blood glucose control in pre-existing diabetes. Insulin resistance and decreased b-cell secretion cause hyperglycemia. Challenges still remain in establishing the connection between COVID-19 and diabetes, whilst the pandemic progresses. Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(2):99-103

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2019冠状病毒病与糖尿病:承认双向联系

COVID-19与糖尿病存在动态的双向关系。糖尿病是covid - 19的一个危险因素。糖尿病与高凝、炎症、高血糖和其他疾病(肥胖、高血压、心血管疾病、慢性肾病)有关。高血糖可能加重SARS-CoV-2感染。由于COVID-19造成的直接胰腺损伤，应激反应是对感染(包括细胞因子风暴)的触发反应，包括使用糖皮质类固醇等高血糖处方药治疗严重的COVID-19，新发高血糖和糖尿病与该病毒有关，以及已经存在的糖尿病患者血糖控制迅速恶化。胰岛素抵抗和b细胞分泌减少引起高血糖。随着大流行的进展，在建立COVID-19与糖尿病之间的联系方面仍然存在挑战。Bangabandhu Sheikh Mujib Med. col。j . 2022; 1 (2): 99 - 103

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Bangabandhu Sheikh Mujib Medical University Journal

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审稿时长

12 weeks