Modified Nutrition Risk in Critically Ill (m-NUTRIC) score to assess nutritional status and outcome in patients of chronic kidney disease: 2-year cross-sectional study

Q4 Medicine
Prerna Verma, Sunil Kumar, Neha Phate, Sourya Acharya, Anil Wanjari, Shilpa Bawankule, Sachin Agrawal
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Abstract

Introduction: Chronic kidney disease (CKD) is a major health concern in India and has high prevalence, morbidity, and mortality due to significant percentages of subjects with poor socioeconomic status as well as poor management of health resources. Many apparatuses are available to assess nutrition status among patients of CKD. This study was conducted to identify nutritional risk in CKD patients using a modified Nutrition Risk in Critically ill (m-NUTRIC) score without using interleukin-6 values. Method: This prospective observational study was conducted at a tertiary care teaching hospital for a time period of 2 years from 2020 to 2022. The modification of diet in renal disease approach was used for the staging of the CKD. m-NUTRIC scores were calculated and scores ≥5 were graded in high-risk categories and were associated with adverse outcomes, whereas scores <5 were categorized as low risk. Result: Among 250 patients with CKD enrolled, 65 patients were in the age group 18 to 40 years having a mean m-NUTRIC score of 4.46 ± 1.76; in the age group 40 to 60 years 5.18 ± 1.67; and in the age group older than 60 years 5.88 ± 1.77. The mean (standard deviation [SD]) m-NUTRIC score in hemodialysis group was 5.69 ± 1.63 and in nonhemodialysis group was 4.15 ± 1.66. At m-NUTRIC cutoff of 5, predicted hemodialysis is having 66% specificity and 77% sensitivity. It predicts mortality with a sensitivity of 93% and a specificity of 89% at a cutoff of m-NUTRIC of 6. Conclusion: This study showed that m-NUTRIC score may be an important tool that determines requirement of hemodialysis and mortality in CKD patients. Moreover, these scores were higher in stages 4 and 5 of CKD.
危重患者改良营养风险(m-NUTRIC)评分评估慢性肾病患者营养状况和预后:2年横断面研究
慢性肾脏疾病(CKD)是印度的主要健康问题,由于社会经济地位低下以及卫生资源管理不善,其患病率、发病率和死亡率都很高。许多仪器可用于评估CKD患者的营养状况。本研究是在不使用白细胞介素-6值的情况下,使用改良的危重症营养风险(m-NUTRIC)评分来确定CKD患者的营养风险。方法:本前瞻性观察研究于2020 - 2022年在某三级保健教学医院进行,为期2年。在CKD的分期中采用了肾脏疾病饮食改变的方法。计算m-NUTRIC评分,得分≥5分为高危类别并与不良结局相关,而得分<5分为低风险类别。结果:在入选的250例CKD患者中,65例患者年龄在18至40岁之间,平均m-NUTRIC评分为4.46±1.76;40 ~ 60岁年龄组5.18±1.67;60岁以上年龄组(5.88±1.77)。血液透析组m-NUTRIC评分均值(标准差[SD])为5.69±1.63,非血液透析组m-NUTRIC评分均值为4.15±1.66。在m-NUTRIC临界值为5时,预测血液透析的特异性为66%,敏感性为77%。在m-NUTRIC的临界值为6时,它预测死亡率的灵敏度为93%,特异性为89%。结论:本研究表明m-NUTRIC评分可能是确定CKD患者血液透析需求和死亡率的重要工具。此外,这些评分在CKD的4期和5期更高。
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
1
期刊介绍: The International Journal of Nutrition, Pharmacology, Neurological Diseases (IJNPND) is an international, open access, peer reviewed journal which covers all fields related to nutrition, pharmacology, neurological diseases. IJNPND was started by Dr. Mohamed Essa based on his personal interest in Science in 2009. This journal doesn’t link with any society or any association. The co-editor-in chiefs of IJNPND (Prof. Gilles J. Guillemin, Dr. Abdur Rahman and Prof. Ross grant) and editorial board members are well known figures in the fields of Nutrition, pharmacology, and neuroscience. First, the journal was started as two issues per year, then it was changed into 3 issues per year and since 2013, it publishes 4 issues per year till now. This shows the slow and steady growth of this journal. To support the reviewers and editorial board members, IJNPND offers awards to the people who does more reviews within one year. The International Journal of Nutrition, Pharmacology, Neurological Diseases (IJNPND) is published Quarterly. IJNPND has three main sections, such as nutrition, pharmacology, and neurological diseases. IJNPND publishes Research Papers, Review Articles, Commentaries, case reports, brief communications and Correspondence in all three sections. Reviews and Commentaries are normally commissioned by the journal, but consideration will be given to unsolicited contributions. International Journal of Nutrition, Pharmacology, Neurological Diseases is included in the UGC-India Approved list of journals.
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