Early Outcome of Off-Pump Versus Conventional Coronary Artery Bypass Grafting Surgery in Patients with Multivessel Coronary Artery Disease in a Specialized center in Bangladesh

Amina Reza, AKM Manzurul Alam, Md Shafiqul Islam, Abdullah Al Mamun Hossain, Md Mizanur Rahman, Md Amirul Islam, Nurul Alam Siddiqi, Md Shahriar Kabir Shimul, M Asmaul Alam Nur, Masud Ahmed, Md Razin Rahman Khan
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Abstract

Background: Both off-pump (OPCAB) and on pump arrest heart coronary artery bypass surgery (CABG) are frequently performed in department of cardiac surgery, NICVD, Dhaka, Bangladesh. Both types of procedures have advantages and disadvantages. This study was conducted to analyze early post-operative outcome following both types of CABG on patients with multivessel coronary artery disease. Methods: Between 1st September 2019 to 28th February 2021, a cross-sectional study was performed with total 60 patients. 30 patients underwent Off Pump coronary artery bypass grafting (OPCAB)(Group A) and 30 patients underwent Conventional Coronary Artery Bypass (CCAB) (Group B) surgery. Preoperative, peroperative and post-operative variables were recorded and analyzed with appropriate statistical tools and p ≤ 0.05 considered statistically significant. Results: Fifty-five male i.e., 91.67% and five female i.e., 8.33% of total patients were participated in this study. Mostly were within forty-five to sixty-four years age group. Preoperative risk factors, family history and drug history had no significant difference (p>0.05). Mean ± SD number of bypass conduits given in each group almost similar and no statistically significant arrhythmia in terms of atrial fibrillation (AF), ventricular tachycardia (VT) and premature ventricular contraction (PVC) were found preoperatively (p>0.05). New onset of early post-operative ECG changes was found in 3 patients of group A and 9 in group B (10 % vs 30%). AF and PVC found in group B significantly (p<0.05) higher than group A. Immediate post-operative troponin I was higher in group B (p = 0.001). Mean ± SD duration of mechanical ventilation, inotropic supports, ICU stay, bleeding and blood transfusion and serum creatinine were significantly higher in group B (p <0.05). Overall immediate and follow up post-operative morbidities were higher in group B than A (p<0.05). Conclusion: Although on pump arrest heart CABG still stands gold standard, in our study we found OPCAB is better than conventional method. Cardiovasc j 2023; 16(1): 1-8
在孟加拉国的一个专业中心,多支冠状动脉疾病患者的非体外循环与常规冠状动脉搭桥术的早期结果
背景:停泵(OPCAB)和停泵心脏冠状动脉搭桥手术(CABG)在孟加拉国达卡NICVD心脏外科经常进行。这两种手术都有优点和缺点。本研究旨在分析两种冠脉搭桥治疗多支冠状动脉疾病患者的早期术后结果。方法:2019年9月1日至2021年2月28日,共60例患者进行横断面研究。30例患者行无泵冠状动脉旁路移植术(OPCAB)(A组),30例患者行常规冠状动脉旁路移植术(CCAB) (B组)。记录术前、术中、术后各项变量,采用相应的统计工具进行分析,p≤0.05为有统计学意义。结果:男性55例,占91.67%,女性5例,占8.33%。大多数人的年龄在45到64岁之间。术前危险因素、家族史、用药史差异无统计学意义(p>0.05)。两组患者搭桥导管平均±SD数基本相似,术前房颤(AF)、室性心动过速(VT)、室性早搏(PVC)均未见有统计学意义的心律失常(p>0.05)。术后早期新发心电图改变A组3例,B组9例(10% vs 30%)。B组AF和PVC明显高于a组(p < 0.05)。B组术后立即肌钙蛋白I明显高于a组(p = 0.001)。B组机械通气时间、肌力支持时间、ICU住院时间、出血输血时间、血清肌酐平均±SD均显著高于对照组(p <0.05)。B组即刻及术后随访总发病率均高于A组(p < 0.05)。结论:虽然泵停心脏冠脉搭桥仍是金标准,但本研究发现OPCAB优于常规方法。心血管病[j] 2023;16 (1): 1 - 8
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