Antimicrobial activity and GCMS Analysis of leaves Extracts of Butea Monosperma Lam Taub

Q3 Pharmacology, Toxicology and Pharmaceutics

Defence Life Science Journal Pub Date : 2023-05-29 DOI:10.14429/dlsj.8.18789

Surabhi Ambastha, Amit Patnaik, Vinay Oraon, Latika Sharan

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引用次数: 0

Abstract

Butea monosperma (Lam.) Taub is a well-known medicinal plant belonging to the family Fabaceae. More than hundreds of plants have been reported in the Ethno-botanical literature of India for theiranti-microbial activity as well as for treatment of many diseases and Butea monosperma (Lam.)Taub is one of them. The present investigation is focused on the anti-microbial activity of Butea monosperma leaves against both gram-positive (Bacillus subtilis, Enterococcus faecalis, Lactobacillus acidophilus, Staphylococcus aureus and Streptococcus mutans) and gram-negative bacteria (Escherichia coli and Pseudomonas aeruginosa) as well as fungi (Candida albicans and Trichophyton rubrum). Both excerpts (ethanol and methanol) show positive responses against all the selected microorganisms. GC-MS analysis is done to find out important compound which is anti-microbial. A total of 38 compounds are identified in GC-MS analysis. Out of 38 compounds, 8 compounds are identified as antimicrobial in nature such as Dodecane, 2-HEXADECEN-1-OL, 3,7,11,15-TETRAMETHYL-, [R-[, Hexadecanoic acid, methyl ester, Phytol, Palmidrol, Squalene, Tetracosane, Vitamin E and Lup-20(29)-en-3-one which justify, this plant possess significant anti-microbial property. GC-MS analysis reveals that majorly, this plant leaves also possess 10 antioxidant compounds (Neophytadiene, 2-HEXADECEN-1-OL, 3,7,11,15-TETRAMETHYL-, [R-[, n-Hexadecanoic acid, Phytol, squalene, .alpha.-Tocospiro B, Tetracosane, .gamma.-Tocopherol, Ergost-5-en-3-ol, (3.beta.)- and STIGMASTA-5,22-DIEN-3-OL, (3.BETA.,22E)-,), 9 anti-cancerous compounds (Hexadecanoic acid, methyl ester, 9,12,15-OCTADECATRIENOIC ACID, METHYL ESTER, squalene, .gamma.-Tocopherol, Vitamin E, Ergost-5-en-3-ol, (3.beta.)-, STIGMASTA- 5,22-DIEN-3-OL, (3.BETA.,22E)-, .gamma.-Sitosterol and Lupeol),8 anti-inflammatory compounds (Neophytadiene,2-HEXADECEN-1-OL, 3,7,11,15-TETRAMETHYL-, [R-[, Hexadecanoic acid, methyl ester, n-Hexadecanoic acid, 9,12,15-OCTADECATRIENOIC ACID, METHYL ESTER, Phytol, Palmidrol, .alpha.-Tocospiro B and Lupeol), 3 cardioprotective compounds ( Neophytadiene, .alpha.-Tocospiro B and .gamma.-Tocopherol A) and 5 antidiabetic compounds (.alpha.-Tocospiro B, Vitamin E, STIGMASTA-5,22-DIEN-3-OL, (3.BETA.,22E)-, .gamma.-Sitosterol and Lup-20(29)-en-3-one).This investigation suggests that this plant leaf has not only anti-microbial potential but also possesses other important compounds to fight against many deadly diseases. Thus, this plant has immense potential to make an individual place in pharmacological industries, especially as antibiotics.

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Butea Monosperma Lam Taub叶提取物的抑菌活性及GCMS分析

但单精子(Lam.)陶布是一种著名的药用植物，属于豆科。在印度的民族植物学文献中报道了数百种植物，因为它们具有抗微生物活性以及治疗许多疾病和Butea monosperma (Lam.)。陶博就是其中之一。本研究主要研究了Butea monosperma叶片对革兰氏阳性菌(枯草芽孢杆菌、粪肠球菌、嗜酸乳杆菌、金黄色葡萄球菌和变形链球菌)和革兰氏阴性菌(大肠杆菌和铜绿假单胞菌)以及真菌(白色念珠菌和红毛癣菌)的抑菌活性。两种提取物(乙醇和甲醇)对所有选定的微生物都有积极的反应。采用气相色谱-质谱分析，找出了重要的抑菌化合物。GC-MS共鉴定出38个化合物。在38个化合物中，鉴定出8个具有抗菌性质的化合物，如十二烷、2-十六烯-1-醇、3,7,11,15-四甲基-、[R-]、十六烷酸、甲酯、叶绿醇、棕榈醇、角鲨烯、四烷、维生素E和lp -20(29)-en-3- 1，证明该植物具有显著的抗菌特性。GC-MS分析显示，该植物叶片还主要含有10种抗氧化化合物(新叶二烯、2-十六烯-1-醇、3,7,11,15-四甲基-、[R-]、n-十六烷酸、叶绿醇、角鲨烯、α)。-Tocospiro B, Tetracosane， γ。-生育酚，麦角-5-烯-3-醇，(3. β)-和污名-5,22-二烯-3-醇，(3. β，22E)-，)， 9种抗癌化合物(十六烷酸甲酯，9,12,15-十八烷三烯酸甲酯，角鲨烯，。-生育酚，维生素E，麦角-5-en-3-醇，(3. β)-，柱头- 5,22- dien -3-醇，(3. β，22E)-， . γ。-谷甾醇和鹿皮醇)，8种抗炎化合物(新植物二烯，2-十六烯-1-醇，3,7,11,15-四甲基-，[R-]，十六烯酸甲酯，正十六烯酸，9,12,15-十八烯三烯酸甲酯，叶绿醇，棕榈醇，α。-Tocospiro B和Lupeol)， 3种心脏保护化合物(新叶藻烯，α。-Tocospiro B和。gamma。-生育酚A)和5种抗糖尿病化合物(。- tocospiro B，维生素E, stigmasta -5,22- dien -3- ol， (3.BETA.，22E)-， .gamma。-谷甾醇和Lup-20(29)-en-3- 1)。这项研究表明，这种植物的叶子不仅具有抗菌潜力，而且还含有其他重要的化合物来对抗许多致命的疾病。因此，这种植物具有巨大的潜力，在药理学工业中占有一席之地，特别是作为抗生素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Defence Life Science Journal Pharmacology, Toxicology and Pharmaceutics-Pharmacology, Toxicology and Pharmaceutics (all)

CiteScore

0.80

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0.00%

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