Ethnicity Affects A1C Levels in Patients With Diagnosed Type 2 Diabetes in Southern Israel

Q3 Medicine

Diabetes Spectrum Pub Date : 2023-09-12 DOI:10.2337/ds23-0009

Yulia Treister-Goltzman, Idit F. Liberty, Roni Peleg

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引用次数: 0

Abstract

Purpose To assess whether ethnicity affects the association between A1C and fasting glucose in people with type 2 diabetes. Methods An epidemiological, cross-sectional study based on computerized medical records of the Southern District of Clalit Health Services. The study population comprised patients ≥40 years of age with type 2 diabetes who underwent blood tests between 8 August 2015 and 20 July 2020. A normal-error multiple linear regression model was used to assess differences in associations among ethnic groups (i.e., Arabs, Ethiopian Jews, and non-Ethiopian Jews) and A1C. Results A total of 59,432 patients with type 2 diabetes were included in the study. Of these, 1,804 were Jews of Ethiopian origin, 49,296 were non-Ethiopian Jews, and 8,332 were Arabs. Compared with non-Ethiopian Jews, A1C levels were increased by 0.1% (1 mmol/mol) among Ethiopian Jews and by 0.3% (3 mmol/mol) among Arabs. Ethnicity was a strong predictor of A1C, explaining 0.6% of its variance. An A1C level of 7% (53 mmol/mol) correlated with fasting glucose levels of 141, 136, and 126 mg/dL in non-Ethiopian Jews, Ethiopian Jews, and Arabs, respectively. Conclusion Ethnic differences in A1C should be considered by clinicians, researchers, and policymakers.

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种族影响以色列南部2型糖尿病患者的A1C水平

目的评估种族是否影响2型糖尿病患者A1C和空腹血糖之间的关系。方法以克拉利特南区卫生服务中心的计算机病历为基础进行流行病学横断面研究。研究人群包括年龄≥40岁的2型糖尿病患者，他们在2015年8月8日至2020年7月20日期间接受了血液检查。采用正态误差多元线性回归模型评估不同族群(即阿拉伯人、埃塞俄比亚犹太人和非埃塞俄比亚犹太人)与糖化血红蛋白相关性的差异。结果共纳入59,432例2型糖尿病患者。其中1 804人为埃塞俄比亚裔犹太人，49 296人为非埃塞俄比亚裔犹太人，8 332人为阿拉伯人。与非埃塞俄比亚犹太人相比，埃塞俄比亚犹太人的A1C水平升高0.1% (1 mmol/mol)，阿拉伯人的A1C水平升高0.3% (3 mmol/mol)。种族是A1C的一个强有力的预测因子，可以解释0.6%的变异。在非埃塞俄比亚犹太人、埃塞俄比亚犹太人和阿拉伯人中，A1C水平为7% (53 mmol/mol)与空腹血糖水平分别为141、136和126 mg/dL相关。结论临床医生、研究人员和政策制定者应考虑A1C的种族差异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetes Spectrum Medicine-Internal Medicine

CiteScore

2.70

自引率

0.00%

发文量

期刊介绍： The mission of Diabetes Spectrum: From Research to Practice is to assist health care professionals in the development of strategies to individualize treatment and diabetes self-management education for improved quality of life and diabetes control. These goals are achieved by presenting review as well as original, peer-reviewed articles on topics in clinical diabetes management, professional and patient education, nutrition, behavioral science and counseling, educational program development, and advocacy. In each issue, the FROM RESEARCH TO PRACTICE section explores, in depth, a diabetes care topic and provides practical application of current research findings.