The Geometric Generalized Birnbaum–Saunders model with long-Term Survivors

Q4 Medicine
Ahmad Reza Baghestani, Farid Zayeri, Mojtaba Meshkat
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 Methods: The Geometric Generalized Birnbaum–Saunders distribution was defined and two useful representations were represented for its density function which contributes to the creation of some mathematical properties. Furthermore, the parameters of the model with cure rate were estimated by using the maximum likelihood method.
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引用次数: 0

Abstract

Introduction: A cure rate survival model was developed based on the assumption that the number of competing reasons for the event of interest has the Geometric distribution and the time allocated to the event of interest follows the Generalized Birnbaum-Saunders distribution. Methods: The Geometric Generalized Birnbaum–Saunders distribution was defined and two useful representations were represented for its density function which contributes to the creation of some mathematical properties. Furthermore, the parameters of the model with cure rate were estimated by using the maximum likelihood method. Results: Several simulations were performed and a real data set was analyzed from the medical area for different sample sizes and censoring percentages.In the melanoma data set and regarding the AIC and SBC selection criteria, the Geometric Generalized Birnbaum–Saunders distribution model was preferred and was selected as the appropriate model in the present study. Conclusion: Geometric Generalized Birnbaum–Saunders distribution is a highly flexible lifetime model which allows for different degrees of Kurtosis and asymmetry.by considering the advantages of the Geometric Generalized Birnbaum–Saunders distribution model, the model can be implemented as an appropriate alternative to explain or predict the survival time for long-term individuals.
具有长期幸存者的几何广义Birnbaum-Saunders模型
导论:建立了一个治愈率生存模型,该模型假定引起感兴趣事件的竞争原因数量具有几何分布,分配给感兴趣事件的时间遵循广义Birnbaum-Saunders分布。 方法:定义了几何广义Birnbaum-Saunders分布,并对其密度函数进行了两种有用的表示,这有助于建立一些数学性质。此外,采用最大似然法对具有固形率的模型参数进行估计。 结果:进行了多次模拟,并对来自医疗领域的真实数据集进行了不同样本量和审查百分比的分析。在黑色素瘤数据集中,AIC和SBC的选择标准,几何广义Birnbaum-Saunders分布模型是首选的,本研究选择几何广义Birnbaum-Saunders分布模型作为合适的模型。 结论:几何广义Birnbaum-Saunders分布是一个高度灵活的寿命模型,它允许不同程度的峰度和不对称性。考虑到几何广义Birnbaum-Saunders分布模型的优点,该模型可以作为解释或预测长期个体生存时间的合适替代方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.80
自引率
0.00%
发文量
26
审稿时长
12 weeks
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