Evaluation of serum progesterone on the day of human chorionic gonadotropin administration as a predictor of pregnancy rate in ICSI

Abstract

Introduction: Increase in serum P4 levels alongside high estradiol (E2) levels may lead to endometrial gland stroma asynchrony, which can lead consequently to implantation failure. Aim: Is to investigate the role of serum progesterone level on the day of hCG administration as a predictor of pregnancy in ICSI. Methods: a prospective observational clinical study main outcome of the study was to evaluate the role of serum progesterone on the day of hCG administration as a predictor of pregnancy rate in ICSI. Results: serum progesterone level at the day of hCG administration is not a useful predictor of pregnancy in cases undergoing ICSI. Conclusion: Serum progesterone at the day of hCG is not a useful predictor of pregnancy outcome. Further studies with larger numbers are needed