Can Vitamin D Positively Impact Sarcopenia Severity Among Older Adults with Hand Osteoarthritis: A Review of the Evidence

Ray Marks
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Abstract

Aim This review examines the research base concerning hand osteoarthritis and changes in muscle mass and quality known as sarcopenia and the possible use of vitamin-D supplementation for reducing this potentially adverse functionally disabling state. Methods Publications detailing a possible link between hand osteoarthritis manifestations and sarcopenia, plus those discussing vitamin D as a possible intervention strategy for minimizing sarcopenia in the older adult were systematically sought and reviewed. Results Collectively, data reveal hand osteoarthritis in the older population is common, and is possibly affected by age as well as disease associated muscle mass declines. Vitamin D, a powerful steroid required by the body to foster many life affirming physiological functions may help reduce the degree of any prevailing sarcopenia and thereby some degree of hand osteoarthritis disability. Conclusions Older individuals with hand osteoarthritis, as well as healthy older adults at risk for sarcopenia are likely to benefit physically from efforts to clarify the extent of this association and if indicated, to examine and intervene thoughtfully to maximize muscle composition as well as safe vitamin D levels where subnormal. Researchers can make highly notable impacts in multiple spheres in this regard and are encouraged to do so.
维生素D能积极影响老年手骨关节炎患者骨骼肌减少症的严重程度吗
目的本综述综述了有关手部骨关节炎和肌肉量和质量变化的研究基础,即肌肉减少症,以及维生素d补充剂可能用于减少这种潜在的不利功能致残状态。方法系统地寻找和回顾了详细描述手骨关节炎表现与肌肉减少症之间可能联系的出版物,以及那些讨论维生素D作为减少老年人肌肉减少症的可能干预策略的出版物。结果总的来说,数据显示老年人群中手骨关节炎是常见的,并且可能受到年龄和疾病相关肌肉质量下降的影响。维生素D是一种强大的类固醇,人体需要它来促进许多肯定生命的生理功能,它可能有助于减轻任何普遍存在的肌肉减少症的程度,从而在一定程度上减轻手骨关节炎的残疾。结论:患有手骨关节炎的老年人,以及有肌肉减少症风险的健康老年人,可能会从澄清这种关联程度的努力中受益,如果有迹象,仔细检查和干预,以最大限度地提高肌肉成分和安全的维生素D水平。研究人员可以在这方面的多个领域产生非常显著的影响,我们鼓励他们这样做。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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