Effect of Palladium acetate as Catalyst on the Synthesis of Novel Isoxazole Derivatives incorporating Carbazole Moiety

Q4 Earth and Planetary Sciences
Rao Ch. Visweswara, Ramanaiah M., Lakshman Shaik
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引用次数: 0

Abstract

Isoxazole and carbazole derivatives have a wide range of biological activity and are of high interest to medicinal chemists. We report the synthesis and characterization of a series of novel isoxazole derivatives which were synthesized by linking the isoxazole moiety to the carbazole nucleus. The process of synthesis and the steps involved in the synthesis of these novel derivates are described in detail in this study. We confirmed the structures of the novel compounds by 1H NMR, 13C NMR, LCMS spectral data as well as by elemental analysis. The antimicrobial activity of newly synthesized compounds was evaluated against bacterial and fungal strains.
醋酸钯催化合成含咔唑基团的新型异恶唑衍生物的影响
异恶唑和咔唑衍生物具有广泛的生物活性,引起了药物化学家的高度兴趣。我们报道了一系列新的异恶唑衍生物的合成和表征,这些衍生物是通过将异恶唑部分与咔唑核连接而合成的。本文详细介绍了这些新型衍生物的合成过程和合成步骤。我们通过1H NMR, 13C NMR, LCMS和元素分析证实了新化合物的结构。新合成的化合物对细菌和真菌的抗菌活性进行了评价。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.50
自引率
0.00%
发文量
195
审稿时长
4-8 weeks
期刊介绍: Information not localized
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